Evidence map›Paper›PMID 38015844›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

A dynamical model of growth and maturation in

John J Tyson, Amirali Monshizadeh, Stanislav Y Shvartsman, Alexander W Shingleton

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Optogenetic control of transition to metamorphosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Food absence is a cue for metamorphosis in the solitary beeProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. A dynamical model of growth and maturation inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

John J TysonDepartment of Biology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.ORCID 0000-0001-7560-6013
Amirali MonshizadehDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607.
Stanislav Y ShvartsmanDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.
Alexander W ShingletonDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607.
University of Illinois Chicago · USPrinceton University · USVirginia Tech · US

Funding

Mechanisms of signal integration in developmental control of organ size and tissue patterningR01HD085870 · NICHD · UNIVERSITY OF MASSACHUSETTS BOSTON · PI VERAKSA, ALEXEY · 2016 to 2020
$1.6M
Mechanisms of signal integration in developmental control of organ size and tissue patterningR01GM141843 · NIGMS · UNIVERSITY OF MASSACHUSETTS BOSTON · PI VERAKSA, ALEXEY · 2021 to 2024
$1.2M
NICHD NIH HHS R01 HD085870NIGMS NIH HHS R01 GM141843
6 · The paper itself

Abstract

The decision to stop growing and mature into an adult is a critical point in development that determines adult body size, impacting multiple aspects of an adult's biology. In many animals, growth cessation is a consequence of hormone release that appears to be tied to the attainment of a particular body size or condition. Nevertheless, the size-sensing mechanism animals use to initiate hormone synthesis is poorly understood. Here, we develop a simple mathematical model of growth cessation in

Indexed as

DrosophilaDrosophila ProteinsAnimalsBody SizeDrosophila melanogasterEcdysoneLarvaMetamorphosis, BiologicalDrosophila ProteinsEcdysonebody sizegrowth cessationhormonal regulationmathematical modelingpuberty

Identifiers

PMID38015844
PMCPMC10710029
OpenAlexW4389078332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.