Evidence map›Paper›PMID 38015507›Full record

ArticleJAMA network open2023

Projected Life Expectancy Gains From Improvements in HIV Care in Black and White Men Who Have Sex With Men.

Katherine M Rich, Ankur Pandya, John J Chiosi, Krishna P Reddy, Fatma M Shebl, Andrea L Ciaranello, Anne M Neilan, Jodian A Pinkney, Elena Losina, Kenneth A Freedberg and 2 more

Abstract read
In one paragraph

Article in JAMA network open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katherine M RichMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Ankur PandyaDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
John J ChiosiMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Krishna P ReddyMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Fatma M SheblMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Andrea L CiaranelloMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Anne M NeilanMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Jodian A PinkneyMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Elena LosinaHarvard Medical School, Boston, Massachusetts.
Kenneth A FreedbergMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Aima A AhonkhaiMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.
Emily P HyleMedical Practice Evaluation Center (MPEC), Massachusetts General Hospital, Boston.

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Spyros A Kalams · 2015 to 2026
$27.5M
Development and application of a new simulation model for COVID-19R01AI042006 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Kenneth Alan Freedberg, Anne Neilan · 1998 to 2026
$12.9M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
The Impact of Hearing Loss Treatment Scale-Up in Persons Aging with HIV on Dementia Risk, Quality of Life, and Healthcare CostsR01AG069575 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYLE, EMILY PARKER · 2021 to 2025
$4.6M
Tobacco Use and Cessation, HIV, and TB in South Africa: Clinical and Economic Outcomes (Clinical and public health approaches to tobacco cessation in South Africa supplement)R01DA050482 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI REDDY, KRISHNA P · 2020 to 2024
$3.4M
Fostering diversity in the next generation of HIV researchers to improve the HIV continuum of careR25MH119857 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2020 to 2024
$1.5M
Diagnosing and preventing HIV infection in adolescents and young adults in the US: clinical impact and cost-effectivenessK08HD094638 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI NEILAN, ANNE · 2018 to 2023
$936k
NIAID NIH HHS P30 AI110527NIAID NIH HHS R01 AI042006NIAID NIH HHS T32 AI007433NIA NIH HHS R01 AG069575NICHD NIH HHS K08 HD094638NIDA NIH HHS R01 DA050482NIMH NIH HHS R25 MH119857
6 · The paper itself

Abstract

Importance: Substantial racial inequities exist across the HIV care continuum between non-Hispanic Black and White men who have sex with men (MSM) in the US. Objectives: To project years of life gained (YLG) with improving the HIV care continuum among Black MSM and White MSM in the US and to determine the outcomes of achieving health equity goals. Design, Setting, and Participants: The Cost-Effectiveness of Preventing AIDS Complications microsimulation model was used and populated with 2021 race-specific data to simulate HIV care among Black MSM and White MSM in the US who have acquired HIV. Analyses were completed from July 2021 to October 2023. Intervention: The study simulated status quo care using race-specific estimates: age at infection, time to diagnosis, receipt of care, and virologic suppression. The study next projected the outcomes of attaining equity-centered vs non-equity-centered goals by simulating 2 equal improvements in care goals: (10-point increased receipt of care and 5-point increased virologic suppression), 3 equity-centered goals (annual HIV testing, 95% receiving HIV care, and 95% virologic suppression) and lastly, an equitable care continuum that achieves annual HIV testing, 95% receiving care, and 95% virologic suppression in Black MSM and White MSM. One-way and multiway sensitivity and scenario analyses were conducted. Main Outcomes and Measures: Mean age at death and YLG. Results: In the simulated cohort, the mean (SD) age at HIV infection was 27.0 (10.8) years for Black MSM and 35.5 (13.6) years for White MSM. In status quo, mean age at death would be 68.8 years for Black MSM and 75.6 years for White MSM. The equal improvements in care goals would result in 0.5 YLG for Black MSM and 0.5 to 0.9 YLG for White MSM. Achieving any 1 equity-centered goal would result in 0.5 to 1.7 YLG for Black MSM and 0.4 to 1.3 YLG for White MSM. With an equitable care continuum compared with the nationally reported status quo, Black MSM and White MSM would gain 3.5 and 2.1 life-years, respectively. If the status quo HIV testing was every 6 years with 75% retained in care and 75% virologically suppressed, Black MSM would gain 4.2 life-years with an equitable care continuum. Conclusions and Relevance: In this simulation modeling study of HIV care goals, equal improvements in HIV care for Black and White MSM maintained or worsened inequities. These results suggest that equity-centered goals for the HIV care continuum are critical to mitigate long-standing inequities in HIV outcomes.

Indexed as

HIV InfectionsSexual and Gender MinoritiesHomosexuality, MaleHumansLife ExpectancyMaleWhite

Identifiers

PMID38015507
PMCPMC10685884

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.