Evidence map›Paper›PMID 38015456›Full record

ArticleEuropean journal of neurology2024

Could motor blocks be a therapeutic option for treatment-resistant functional dystonia? A case series of three patients.

Béatrice Garcin, Amaury Cinquin, Bertrand Degos, Emmanuel Roze, Alexis Schnitzler

Open access · hybridAbstract readCase Reports
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Béatrice GarcinNeurology Department of Avicenne Hospital, APHP, Bobigny, France.ORCID 0000-0001-9109-9904
Amaury CinquinNeurology Department of Avicenne Hospital, APHP, Bobigny, France.
Bertrand DegosNeurology Department of Avicenne Hospital, APHP, Bobigny, France.
Emmanuel RozeNeurology Department of Pitié Salpétrière Hospital, APHP, Paris, France.
Alexis SchnitzlerPhysical Medicine and Rehabilitation Department of Lariboisière-Fernand Widal hospital, APHP, Paris, France.
Université Sorbonne Paris Nord · FRAssistance Publique – Hôpitaux de Paris · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of functional dystonia is challenging because it is difficult to distinguish functional dystonia from other types of dystonia. After diagnostic explanation, multidisciplinary care is recommended, but some patients are resistant to treatments. We used motor blocks in three patients with severe resistant functional dystonia of the upper limbs to test (i) whether joint contracture was present and (ii) whether motor blocks have a therapeutic effect on functional dystonia. Patient 1 showed a good and sustained therapeutic response, Patient 2 experienced a resolution of the dystonic posture that lasted for 10 days, and Patient 3 experienced no effect. Motor blocks may be a useful therapeutic option in chronic treatment-resistant functional dystonia. The treatment effect might be achieved through the experience of normal positioning and functioning of the limb.

Indexed as

DystoniaDystonic DisordersMovement DisordersHumansUpper ExtremityFNDfunctional dystoniamotor blocksresistant chronic functional dystoniatreatment

Identifiers

PMID38015456
PMCPMC11235907
OpenAlexW4389078097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.