Evidence map›Paper›PMID 38015360›Full record

Trial reportProbiotics and antimicrobial proteins2025

Distinct Microbial Taxa Are Associated with LDL-Cholesterol Reduction after 12 Weeks of Lactobacillus plantarum Intake in Mild Hypercholesterolemia: Results of a Randomized Controlled Study.

Felix Kerlikowsky, Mattea Müller, Theresa Greupner, Lena Amend, Till Strowig, Andreas Hahn

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Effect of Probiotics ContainingFoods (Basel, Switzerland) · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Felix Kerlikowsky *Institute of Food Science and Human Nutrition, Leibniz University Hannover, 30167, Hannover, Germany. kerlikowsky@nutrition.uni-hannover.de.
Mattea Müller *Institute of Food Science and Human Nutrition, Leibniz University Hannover, 30167, Hannover, Germany.
Theresa GreupnerInstitute of Food Science and Human Nutrition, Leibniz University Hannover, 30167, Hannover, Germany.
Lena AmendDepartment of Microbial Immune Regulation, Helmholtz Center for Infection Research, Brunswick, Germany.
Till StrowigDepartment of Microbial Immune Regulation, Helmholtz Center for Infection Research, Brunswick, Germany.
Andreas HahnInstitute of Food Science and Human Nutrition, Leibniz University Hannover, 30167, Hannover, Germany.
Leibniz University Hannover · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic microbes such as Lactobacillus may reduce serum total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol. The objective of this study was to assess the effect of Lactobacillus plantarum strains CECT7527, CECT7528, and CECT7529 (LP) on the serum lipids, cardiovascular parameters, and fecal gut microbiota composition in patients with mild hypercholesterolemia. A randomized, double-blinded, placebo-controlled clinical trial with 86 healthy adult participants with untreated elevated LDL cholesterol ≥ 160 mg/dl was conducted. Participants were randomly allocated to either placebo or LP (1.2 × 10

Indexed as

Cholesterol, LDLGastrointestinal MicrobiomeHypercholesterolemiaLactiplantibacillus plantarumProbioticsAdultAgedBacteriaDouble-Blind MethodFecesFemaleHumansMaleMiddle AgedCholesterol, LDLDyslipidemiaGut microbiotaLow-density lipoproteinProbiotic

Identifiers

PMID38015360
PMCPMC12055864
OpenAlexW4389089787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.