SynthesisActa neurologica Belgica2024
Prognostic factors for falls in Parkinson's disease: a systematic review.
Synthesis in Acta neurologica Belgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Pooled it
- Cognitive markers of resilience to dementia in mild Neurocognitive Impairment: a meta- analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Anti-osteoporosis medications in persons with and without Parkinson disease in Finland.Archives of osteoporosis · 2026Article
- Associations Between Objective, Functional, and Self-Reported Balance Assessments and Fall Frequency in Parkinson's Disease.Irish journal of medical science · 2026Article
- Closing the Gate Before the Horse is out of the Barn: A Model to Effectively Predict the First Fall in Patients with Parkinson's Disease.Movement disorders clinical practice · 2026Article
- A machine learning approach to quantifying fall conversion risk in fall-naïve Parkinson's patients.Parkinsonism & related disorders · 2026Article
- The central cholinergic system as a therapeutic target in Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Classification of fallers in Parkinson's disease through machine learning based feature analysis.NPJ Parkinson's disease · 2026Article
- Assessment of Fall Risk in Neurological Disorders and Technology: Relationship Between Silver Index and Gait Analysis.Sensors (Basel, Switzerland) · 2026Article
- Cross-sectional stratification of fall-related vulnerability in Parkinson's disease through multimodal fusion of speech, gait, facial expression, and upper-limb movement.Frontiers in digital health · 2026Article
- Development and validation of a clinical prediction model for first fall in early Parkinson's disease: a study of two fall-naive cohorts.Frontiers in aging neuroscience · 2026Article
- Foot placement coordination is impaired in people with Parkinson's disease.Journal of neuroengineering and rehabilitation · 2025Article
- Article
- Lower limb motor effects of DBS neurofeedback in Parkinson's disease assessed through IMU-based UPDRS movement quality metrics.Scientific reports · 2025Article
- Incidence of hip fractures in persons with and without Parkinson's disease in Finland: a 15-year longitudinal study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Feasibility of a Community-Based Boxing Program with Tailored Balance Training in Parkinson's Disease: A Preliminary Study.Brain sciences · 2025Article
- Machine Learning Predicts Risk of Falls in Parkison's Disease Patients in a Multicenter Observational Study.European journal of neurology · 2025Observational
- Cognitive measures predict falls in Parkinson's disease: Insights from the CYCLE-II cohort.Parkinsonism & related disorders · 2025Article
- Cueing-assisted gamified augmented-reality gait-and-balance rehabilitation at home for people with Parkinson's disease: protocol of a pragmatic randomized controlled trial implemented in the clinical pathway.Frontiers in neurology · 2025Article
- Relationship of foot pain with the increased risk of falls in patients with Parkinson's disease.Journal of foot and ankle research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFalls represent a critical concern in Parkinson's disease (PD), contributing to increased morbidity and reduced quality of life. PURPOSE: We conducted a systematic review to assess the prognostic factors associated with falls in PD, aiming to provide a comprehensive overview of relevant demographic and clinical parameters, and aid neurologists in identifying subsets of PD patients most susceptible to falls and associated injuries.
methodsPubMed and Web of Science databases were searched for prospective studies assessing factors associated with falls in ambulatory PD patients across different settings, from inception to August 2023. Data extraction was conducted using CHARMS-PF checklist and risk of bias was assessed with QUIPS tool. PRISMA guidelines were followed.
resultsThe initial search yielded 155 references. Thirty-four studies, involving a total of 3454 PD patients, were included in the final analysis. The mean pooled age was 67.6 years, and 45.1% were women. PD patients presented mild motor impairment (UPDRS III score 27.8) with mean pooled disease duration of 5.7 years. Gait and balance disorders and history of prior falls emerged as the most consistent predictors of falls across studies. Disease duration, disease severity, dysautonomic symptoms, freezing of gait, frontal cognitive functions, and PD medication dosages yielded inconsistent findings. Conversely, dyskinesias, age, sex, and depression were unrelated to future falls in PD. Logistic regression models were most commonly employed to identify factors significantly associated with falls in PD. Substantial heterogeneity prevailed in the inclusion of confounding factors.
conclusionThe evidence suggests that previous history of falls, gait disorders, and poor balance are robust prognostic markers for falls in PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.