Evidence map›Paper›PMID 38015167›Full record

ArticleTranslational vision science & technology2023

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop.

S Robert Levine, Martin G Myers, Ryan Barunas, Dolly S Chang, Sanjoy Dutta, Ted Maddess, Jeffrey M Liebmann, Steve Sherman, Melvina Eydelman, Jennifer K Sun and 8 more

Abstract read
In one paragraph

Article in Translational vision science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

S Robert LevineMary Tyler Moore Vision Initiative, Greenwich, CT, USA.
Martin G MyersUniversity of Michigan Caswell Diabetes Institute, Ann Arbor, MI, USA.
Ryan BarunasJDRF Northeast Ohio & Michigan Chapter, Southfield, MI, USA.
Dolly S ChangGenentech, South San Francisco, CA, USA.
Sanjoy DuttaJDRF, New York, NY, USA.
Ted MaddessJohn Curtin School of Medical Research, Australian National University, Canberra, Australia.
Jeffrey M LiebmannEdward S. Harkness Eye Institute, Columbia University Medical Center, New York, NY, USA.
Steve ShermanRegeneron Pharmaceuticals, Tarrytown, NY, USA.
Melvina EydelmanFood and Drug Administration, Rockville, MD, USA.
Jennifer K SunJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Wiley ChambersFood and Drug Administration, Silver Spring, MD, USA.
Kerstin WickströmIcelandic Medicines Agency, Reykjavik, Iceland.
Ulrich F O LuhmannRoche Pharmaceutical Research and Early Development, Translational Medicine Ophthalmology, Roche Innovation Center, Basel, Switzerland.
Martin PallinatVisiontree Software, Inc., San Diego, CA, USA.
Adam GlassmanJaeb Center for Health Research, Tampa, FL, USA.
Lloyd Paul AielloJoslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Dorene S MarkelDepartment of Learning Health Sciences, University of Michigan, Ann Arbor, MI, USA.
Thomas W GardnerMary Tyler Moore Vision Initiative, Greenwich, CT, USA.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

The Mary Tyler Moore Vision Initiative Diabetic Retinal Disease (DRD) Clinical Endpoints Workshop was held on October 22, 2022 to accelerate progress toward establishment of useful clinical and research endpoints and development of new therapeutics that have important relevance across the full spectrum of DRD pathology. More than 90 patient representatives, clinicians, scientists, funding and regulatory agencies, diagnostic, therapeutic and biotech industry representatives discussed the needs for new diagnostic and therapeutic approaches to prevent and restore retinal neurovascular unit integrity. Phase I of the MTM Vision Initiative plans, notably updating the DRD staging system and severity scale, establishing a human ocular biorepository and resource, and clinical endpoints and biomarker development and validation, was emphasized.

Indexed as

Diabetes MellitusDiabetic RetinopathyHumansRetina

Identifiers

PMID38015167
PMCPMC10691397

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.