Evidence map›Paper›PMID 38014980›Full record

ArticleMicrobiology spectrum2024

SalivaDirect: an alternative to a conventional RNA extraction protocol for molecular detection of SARS-CoV-2 in a clinical setting.

Mohammad Khaja Mafij Uddin, Mohammad Enayet Hossain, Jenifar Quaiyum Ami, Rashedul Hasan, Md Mahmudul Hasan, Ashabul Islam, Md Jahid Hasan, Nusrat Jahan Shaly, Shahriar Ahmed, Pushpita Samina and 3 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mohammad Khaja Mafij UddinInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.ORCID 0000-0003-1792-5950
Mohammad Enayet HossainInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.ORCID 0000-0001-5511-1857
Jenifar Quaiyum AmiInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Rashedul HasanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Md Mahmudul HasanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Ashabul IslamInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Md Jahid HasanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Nusrat Jahan ShalyNutrition and Clinical Services Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Shahriar AhmedInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Pushpita SaminaCentre for Health Economics and Policy Analysis, McMaster University , Hamilton, Ontario, Canada.
Mohammed Ziaur RahmanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.
Mustafizur RahmanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.ORCID 0000-0002-6876-0191
Sayera BanuInfectious Diseases Division, International Centre for Diarrhoeal Disease Research , Dhaka, Bangladesh.ORCID 0000-0002-5121-1962

Funding

United States Agency for International Development (USAID) 72038820CA00002
6 · The paper itself

Abstract

importanceAffordable and accessible tests for COVID-19 allow for timely disease treatment and pandemic management. SalivaDirect is a faster and easier method to implement than NPS sampling. Patients can self-collect saliva samples at home or in other non-clinical settings without the help of a healthcare professional. Sample processing in SalivaDirect is less complex and more adaptable than in conventional nucleic acid extraction methods. We found that SalivaDirect has good diagnostic performance and is ideal for large-scale testing in settings where supplies may be limited or trained healthcare professionals are unavailable.

Indexed as

COVID-19SARS-CoV-2Health PersonnelHumansPandemicsRNASalivaSpecimen HandlingRNACOVID-19Nasopharyngeal swabRT-qPCRSalivaSalivaDirectSARS-CoV-2

Identifiers

PMID38014980
PMCPMC10783095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.