Evidence map›Paper›PMID 38014956›Full record

ArticleApplied and environmental microbiology2023

MmoD regulates soluble methane monooxygenase and methanobactin production in

Peng Peng, Junwon Yang, Alan A DiSpirito, Jeremy D Semrau

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Peng PengDepartment of Civil and Environmental Engineering, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-9982-5210
Junwon YangDepartment of Civil and Environmental Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Alan A DiSpiritoRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, USA.ORCID 0000-0003-3602-6213
Jeremy D SemrauDepartment of Civil and Environmental Engineering, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-1670-9984
University of Michigan · USIowa State University · US

Funding

National Science Foundation (NSF) 1912482U.S. Department of Energy (DOE) DE-SC0020174
6 · The paper itself

Abstract

importanceAerobic methanotrophs play a critical role in the global carbon cycle, particularly in controlling net emissions of methane to the atmosphere. As methane is a much more potent greenhouse gas than carbon dioxide, there is increasing interest in utilizing these microbes to mitigate future climate change by increasing their ability to consume methane. Any such efforts, however, require a detailed understanding of how to manipulate methanotrophic activity. Herein, we show that methanotrophic activity is strongly controlled by MmoD, i.e., MmoD regulates methanotrophy through the post-transcriptional regulation of the soluble methane monooxygenase and controls the ability of methanotrophs to collect copper. Such data are likely to prove quite useful in future strategies to enhance the use of methanotrophs to not only reduce methane emissions but also remove methane from the atmosphere.

Indexed as

Methylosinus trichosporiumCopperImidazolesMethaneOligopeptidesOxygenasesCopperImidazolesMethanemethane monooxygenasemethanobactinOligopeptidesOxygenasescoppermethane monooxygenasemethanobactinmethanotrophyMmoD

Identifiers

PMID38014956
PMCPMC10734442
OpenAlexW4389084984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.