Evidence map›Paper›PMID 38014943›Full record

ArticleAntimicrobial agents and chemotherapy2023

Case Commentary: Another prong of attack? Topical antibiotic instillation with negative pressure wound therapy for nontuberculous mycobacterial skin and soft tissue infections.

David C Nguyen, Angel M Buettner, Khalid M Dousa

Abstract readComment
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Antimicrobial agents and chemotherapy · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

David C NguyenDepartment of Pediatrics, Division of Pediatric Infectious Diseases, Rush Medical College, Chicago, Illinois, USA.ORCID 0000-0001-5738-2976
Angel M BuettnerDepartment of Hyperbaric Medicine and Wound Care, Advocate Aurora Healthcare System, Sheboygan, Wisconsin, USA.
Khalid M DousaDepartment of Medicine, Case Western Reserve University and Medicine Service, Veterans Affairs Northeast Ohio Healthcare System, Cleveland, Ohio, USA.ORCID 0000-0003-3272-7231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nontuberculous mycobacteria (NTM) skin infections remain therapeutically challenging. Given the diversity in infections, host responses, and antimicrobials, clinical guidelines are often built on case series and observational studies. In this commentary, we respond to a paper by Stemkens et al. that introduces an emerging strategy: adjunctive negative pressure wound therapy with instillation and dwell time combined with topical antibiotics for refractory NTM skin and soft tissue infections. We delve into the primary considerations surrounding this innovative approach.

Indexed as

Mycobacterium Infections, NontuberculousNegative-Pressure Wound TherapySkin Diseases, BacterialSoft Tissue InfectionsAnti-Bacterial AgentsHumansNontuberculous MycobacteriaAnti-Bacterial AgentsMycobacteriumnegative pressure wound therapyskin and soft tissue Infectionwound

Identifiers

PMID38014943
PMCPMC10720531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.