Evidence map›Paper›PMID 38014727›Full record

ArticleInfection & chemotherapy2024

Usefulness of the Rapid Antigen Test in Detecting SARS-CoV-2 for Infection Control in Hospitals.

Jeong Young Lee, Jiwon Jung, Jae Lim Jo, Young-Ju Lim, Sun-Kyung Kim, Hyejin Yang, Soyeon Park, Eun Ok Kim, Sung-Han Kim

Open access · goldAbstract read
In one paragraph

Article in Infection & chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jeong Young Lee *Office of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-4254-3818
Jiwon Jung *Office of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-4333-3270
Jae Lim JoOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0009-0009-0274-6395
Young-Ju LimOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-8529-2676
Sun-Kyung KimOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-6063-488X
Hyejin YangOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0009-0008-1407-0655
Soyeon ParkOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7850-6373
Eun Ok KimOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-5957-5421
Sung-Han KimOffice of Infection Control, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-6596-8253
Asan Medical Center · KRUlsan College · KR

Funding

Korea National Institute of Health HD22C2045National Research Foundation of Korea RS-2023-00219002
6 · The paper itself

Abstract

backgroundWe aimed at evaluating the diagnostic performance of rapid antigen test (RAT) compared to polymerase chain reaction (PCR) for severe acute respiratory syndrome coronavirus 2 and the possible transmission of infection to close contacts from patients with negative RAT and positive PCR results. MATERIALS AND

methodsPatients/guardians urgently requiring admission to the ward on the same day had been hospitalized with RAT-negative result before the PCR results were available. We performed an epidemiologic investigation of the close contacts of those with negative RAT but positive PCR results after hospitalization.

resultsA total of 4,237 RATs were performed from March to August 2022. When the PCR test was used as the reference, RAT had a sensitivity of 28.8% (17/59; 95% confidence interval [CI], 17.8 - 42.1), a specificity of 100% (4,220/4,220; 95% CI, 99.9 - 100.0), a positive predictive value of 100.0% (17/17; 95% CI, 100.0 - 100.0), and a negative predictive value of 99.0% (4,178/4,220; 95% CI, 99.3 - 99.8). The epidemiologic investigation revealed that among the 32 patients with negative RAT and subsequent positive PCR results after admission into multi-patient room, two (6.3%) showed secondary coronavirus disease 2019.

conclusionThe secondary transmission rate from patients with negative RAT and positive PCR results was low. Our data suggest that RAT may be useful for rapid exclusion of high transmissible cases. However, further evaluation using whole genome sequencing is needed to determine the potential for transmissibility in cases showing a negative RAT but a positive PCR result.

Indexed as

Contact tracingCOVID-19Infection controlRapid diagnostic test

Identifiers

PMID38014727
PMCPMC10990885
OpenAlexW4388962026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.