Evidence map›Paper›PMID 38014671›Full record

ArticleJournal of the American Heart Association2023

Short- and Long-Term Mortality for Patients With and Without a Cancer Diagnosis Following Pulmonary Embolism in Denmark, 2000 to 2020: A Nationwide Study.

Sophie Fredslund Madsen, Daniel Mølager Christensen, Jarl Emanuel Strange, Nina Nouhravesh, Thomas Kümler, Gunnar Gislason, Morten Lamberts, Caroline Sindet-Pedersen

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sophie Fredslund MadsenDepartment of Cardiology, Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark.ORCID 0000-0002-9079-0530
Daniel Mølager ChristensenDanish Heart Foundation Copenhagen Denmark.ORCID 0000-0003-4029-1060
Jarl Emanuel StrangeDepartment of Clinical Medicine, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark.ORCID 0000-0002-1803-5266
Nina NouhraveshDepartment of Clinical Medicine, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark.ORCID 0000-0002-4891-7358
Thomas KümlerDepartment of Clinical Medicine, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark.ORCID 0000-0001-9102-3862
Gunnar GislasonDepartment of Cardiology, Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark.ORCID 0000-0002-0548-402X
Morten LambertsDepartment of Cardiology, Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark.ORCID 0000-0002-9827-440X
Caroline Sindet-PedersenDanish Heart Foundation Copenhagen Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew treatment regimens have been introduced in the past 20 years, which may influence the short- and long-term prognosis for patients with and without a cancer diagnosis following pulmonary embolism. However, newer studies investigating these trends are lacking. Therefore, we aimed to investigate the 30- and 31- to 365-day mortality following pulmonary embolism. METHODS AND

resultsUsing the Danish nationwide registries, patients with a diagnosis of pulmonary embolism between 2000 and 2020 were included. Age- and sex-standardized 30- and 31- to 365-day mortality was calculated and stratified by cancer status. In total, 60 614 patients (29.6% with recent cancer; mean age, 68.2 years) were included. The 30-day mortality for patients with no recent cancer decreased from 19.1% (95% CI, 17.9%-20.4%) in 2000 to 7.3% (95% CI, 6.7%-8.0%) in 2018 to 2020 (hazard ratio [HR], 0.36 [95% CI, 0.32-0.40];

conclusionsFrom 2000 to 2020, improvements were observed in 30-day mortality following pulmonary embolism regardless of cancer status. For patients with recent cancer, 31- to 365-day mortality did not improve, whereas a minor improvement was observed for patients without recent cancer.

Indexed as

NeoplasmsPulmonary EmbolismAgedDenmarkHumansPrognosisProportional Hazards Modelsantithrombotic therapyepidemiologynon–vitamin K oral anticoagulantpulmonary embolism

Identifiers

PMID38014671
PMCPMC10727333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.