Evidence map›Paper›PMID 38014449›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2024

Repurposing dried blood spot device technology to examine bile acid profiles in human dried fecal spot samples.

Melinda A Engevik, Santosh Thapa, Ian M Lillie, Mary Beth Yacyshyn, Bruce Yacyshyn, Andrew J Percy, Donald Chace, Thomas D Horvath

Abstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. mSphere · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melinda A EngevikDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina, United States.ORCID 0000-0002-9742-9932
Santosh ThapaDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States.ORCID 0000-0002-4534-1349
Ian M LillieDepartment of Materials Science & Engineering, Cornell University, Ithaca, New York, United States.ORCID 0009-0002-4509-9350
Mary Beth YacyshynDivision of Digestive Diseases, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.ORCID 0000-0002-3910-7812
Bruce YacyshynDivision of Digestive Diseases, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.ORCID 0000-0003-3472-6697
Andrew J PercyDepartment of Applications Development, Cambridge Isotope Laboratories, Inc., Tewksbury, Massachusetts, United States.
Donald ChaceCapitainer, Stockholm, Sweden.
Thomas D HorvathDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States.ORCID 0000-0001-9761-3484

Funding

Identifying the role of serotonin receptor 4 and trefoil factor 3 in intestinal wound repairK01DK123195 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ENGEVIK, MELINDA ANNE · 2020 to 2024
$612k
NIDDK NIH HHS K01 DK123195
6 · The paper itself

Abstract

Dried blood spot (DBS) analysis has existed for >50 years, but application of this technique to fecal analysis remains limited. To address whether dried fecal spots (DFS) could be used to measure fecal bile acids, we collected feces from five subjects for each of the following cohorts:

Indexed as

Dry IceTandem Mass SpectrometryBile Acids and SaltsChromatography, LiquidHumansTechnologyBile Acids and SaltsDry Icebile acidsdried blood spotdried fecal spotfecesLC-MS/MS

Identifiers

PMID38014449
PMCPMC11208030

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.