Evidence map›Paper›PMID 38014378›Full record

ArticleCHEST critical care2023

Early Serial Echocardiographic and Ultrasonographic Findings in Critically Ill Patients With COVID-19.

Michael J Lanspa, Siddharth P Dugar, Heather L Prigmore, Jeremy S Boyd, Jordan D Rupp, Chris J Lindsell, Todd W Rice, Nida Qadir, George W Lim, Ariel L Shiloh and 23 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CHEST critical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 10 institutions in 1 country.

Michael J LanspaShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Siddharth P DugarCleveland Clinic, Cleveland, OH.
Heather L PrigmoreVanderbilt Comprehensive Care Clinic, Nashville, TN.
Jeremy S BoydVanderbilt Health, Vanderbilt University, Nashville, TN.
Jordan D RuppVanderbilt Health, Vanderbilt University, Nashville, TN.
Chris J LindsellVanderbilt Comprehensive Care Clinic, Nashville, TN.
Todd W RiceVanderbilt Comprehensive Care Clinic, Nashville, TN.
Nida QadirUniversity of California, Los Angeles, Los Angeles, CA.
George W LimUniversity of California, Los Angeles, Los Angeles, CA.
Ariel L ShilohMontefiore Medical Center, New York, NY.
Vladyslav DieievMontefiore Medical Center, New York, NY.
Michelle N GongMontefiore Medical Center, New York, NY.
Steven W FoxCleveland Clinic, Cleveland, OH.
Eliotte L HirshbergShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Akram KhanOregon Health and Science University, Portland, OR.
James KornfieldOregon Health and Science University, Portland, OR.
Jacob H SchoeneckWake Forest University, Winston-Salem, NC.
Nicholas MacklinWake Forest University, Winston-Salem, NC.
D Clark FilesWake Forest University, Winston-Salem, NC.
Kevin W GibbsWake Forest University, Winston-Salem, NC.
Matthew E PrekkerHennepin County Medical Center, Minneapolis, MN.
Daniel Parsons-MossHennepin County Medical Center, Minneapolis, MN.
Mikaele BownShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Troy D OlsenShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Daniel B KnoxShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Meghan M CirulisShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Omar MehkriCleveland Clinic, Cleveland, OH.
Abhijit DuggalCleveland Clinic, Cleveland, OH.
Mark W TenfordeCenters for Disease Control and Prevention, Atlanta, GA.
Manish M PatelCenters for Disease Control and Prevention, Atlanta, GA.
Wesley H SelfVanderbilt Comprehensive Care Clinic, Nashville, TN.
Samuel M BrownShock Trauma ICU, Intermountain Medical Center, Salt Lake City, UT.
Influenza and Other Viruses in the Acutely Ill Network
Intermountain Medical Center · USCleveland Clinic · USVanderbilt University · USWake Forest University · USMontefiore Medical Center · USCenters for Disease Control and Prevention · USHennepin County Medical Center · USOregon Health & Science University · USUniversity of California, Los Angeles · USVanderbilt Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac function of critically ill patients with COVID-19 generally has been reported from clinically obtained data. Echocardiographic deformation imaging can identify ventricular dysfunction missed by traditional echocardiographic assessment. Research Question: What is the prevalence of ventricular dysfunction and what are its implications for the natural history of critical COVID-19? Study Design and Methods: This is a multicenter prospective cohort of critically ill patients with COVID-19. We performed serial echocardiography and lower extremity vascular ultrasound on hospitalization days 1, 3, and 8. We defined left ventricular (LV) dysfunction as the absolute value of longitudinal strain of < 17% or left ventricle ejection fraction (LVEF) of < 50%. Primary clinical outcome was inpatient survival. Results: We enrolled 110 patients. Thirty-nine (35.5%) died before hospital discharge. LV dysfunction was present at admission in 38 patients (34.5%) and in 21 patients (36.2%) on day 8 ( Interpretation: Among patients with critical COVID-19, LV and RV dysfunction is common, frequently identified only through deformation imaging, and early (day 1) RV dysfunction may be associated with clinical outcome.

Indexed as

COVID-19echocardiographypoint-of-care ultrasoundstrainultrasound

Identifiers

PMID38014378
PMCPMC10030437
OpenAlexW4353096525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.