Evidence map›Paper›PMID 38014313›Full record

ArticlebioRxiv : the preprint server for biology2023

Identifying genetic variants that influence the abundance of cell states in single-cell data.

Laurie Rumker, Saori Sakaue, Yakir Reshef, Joyce B Kang, Seyhan Yazar, Jose Alquicira-Hernandez, Cristian Valencia, Kaitlyn A Lagattuta, Annelise Mah-Som, Aparna Nathan and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Laurie RumkerCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Saori SakaueCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Yakir ReshefCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Joyce B KangCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Seyhan YazarTranslational Genomics, Garvan Institute of Medical Research, Sydney, Australia.
Jose Alquicira-HernandezCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Cristian ValenciaCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Kaitlyn A LagattutaCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Annelise Mah-SomDivision of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Aparna NathanCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Joseph E PowellTranslational Genomics, Garvan Institute of Medical Research, Sydney, Australia.
Po-Ru LohCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
Soumya RaychaudhuriCenter for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-1901-8265

Funding

Role of fibroblastic stromal cells and notch signaling in tissue inflammation in RA and SLEP01AI148102 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael B. Brenner, Nir Hacohen · 2021 to 2026
$17.3M
Training Program in Bioinformatics and Integrative GenomicsT32HG002295 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Peter J Park · 2001 to 2026
$15.8M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Discovery and Functional Impact of Common and Rare Variants in RAR01AR063759 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Soumya Raychaudhuri · 2013 to 2026
$5.4M
Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC)UC2AR081023 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Soumya Raychaudhuri · 2022 to 2026
$4.8M
Predicting the impact of genetic variants, genes and pathways on human DiseaseU01HG012009 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI ALKES L PRICE, Soumya Raychaudhuri · 2021 to 2026
$4.2M
Integrative modelling of single-cell data to elucidate the genetic architecture of complex diseaseR56HG013083 · NHGRI · DANA-FARBER CANCER INST · PI GUSEV, ALEXANDER, PRICE, ALKES L · 2023 to 2023
$400k
Characterizing the Genomic Basis of Immune-Mediated Resilience Against Tuberculosis in an Admixed Peruvian PopulationF30AI157385 · NIAID · HARVARD MEDICAL SCHOOL · PI RUMKER, LAURIE ANN · 2021 to 2024
$178k
Pinpointing how single-cell states affect genetic regulation of HLA expression in autoimmune diseasesF30AI172238 · NIAID · HARVARD MEDICAL SCHOOL · PI KANG, JOYCE BLOSSOM · 2022 to 2024
$143k
NHGRI NIH HHS R56 HG013083NHGRI NIH HHS T32 HG002295NHGRI NIH HHS U01 HG012009NIAID NIH HHS F30 AI157385NIAID NIH HHS F30 AI172238NIAID NIH HHS P01 AI148102NIAMS NIH HHS R01 AR063759NIAMS NIH HHS UC2 AR081023NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38014313
PMCPMC10680752

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.