ArticlebioRxiv : the preprint server for biology2023
AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans.
Brendan J Houston, Joseph Nguyen, D Jo Merriner, Anne E O'Connor, Alexandra M Lopes, Liina Nagirnaja, Corinna Friedrich, Sabine Kliesch, Frank Tüttelmann, Kenneth I Aston and 4 more
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
14 authors at 6 institutions in 4 countries.
Brendan J HoustonSchool of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Australia.ORCID 0000-0002-1078-756X Joseph NguyenSchool of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Australia.
D Jo MerrinerSchool of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Australia.
Anne E O'ConnorSchool of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Australia.
Alexandra M Lopesi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
Liina NagirnajaDivision of Genetics, Oregon National Primate Research Center, Beaverton, USA.
Corinna FriedrichInstitute of Reproductive Genetics, University of Münster, Münster, Germany.
Sabine KlieschCentre of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.
Kenneth I AstonGenetics of Male Infertility Initiative (GEMINI) consortium.
Robin M HobbsCentre for Reproductive Health, Hudson Institute of Medical Research, Monash University, Clayton, Australia.
Jessica Em DunleavySchool of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Australia.ORCID 0000-0003-2009-0165 Moira K O'BryanSchool of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Australia.ORCID 0000-0001-7298-4940 The University of Melbourne · AUUniversity of Münster · DEOregon National Primate Research Center · USHudson Institute of Medical Research · AUUniversidade do Porto · PTUniversity of Utah · US
Funding
GENOMICS OF SPERMATOGENIC IMPAIRMENTR01HD078641 · NICHD · WASHINGTON UNIVERSITY · PI Kenneth Ivan Aston, DONALD F. CONRAD · 2014 to 2026
$6.3MNICHD NIH HHS R01 HD078641
6 · The paper itselfAbstract
Dynein complexes are large, multi-unit assemblies involved in many biological processes including male fertility via their critical roles in protein transport and axoneme motility. Previously we identified a pathogenic variant in the dynein gene
Indexed as
Dyneinmale infertility geneticsprotein transportspermatogonia
Identifiers
PMID38014244
PMCPMC10680566
OpenAlexW4388384234
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
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