Evidence map›Paper›PMID 38014107›Full record

ArticlebioRxiv : the preprint server for biology2023

A Multi-task Platform for Profiling Cognitive and Motivational Constructs in Humans and Nonhuman Primates.

Marcus R Watson, Nathan Traczewski, Seema Dunghana, Kianoush Banaie Boroujeni, Adam Neumann, Xuan Wen, Thilo Womelsdorf

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marcus R WatsonDep. of Psychology, Vanderbilt University, Nashville, TN 37240.
Nathan TraczewskiDep. of Psychology, Vanderbilt University, Nashville, TN 37240.
Seema DunghanaDep. of Psychology, Vanderbilt University, Nashville, TN 37240.
Kianoush Banaie BoroujeniDep. of Psychology, Vanderbilt University, Nashville, TN 37240.ORCID 0000-0002-2323-0648
Adam NeumannDep. of Psychology, Vanderbilt University, Nashville, TN 37240.
Xuan WenDep. of Psychology, Vanderbilt University, Nashville, TN 37240.
Thilo WomelsdorfDep. of Psychology, Vanderbilt University, Nashville, TN 37240.ORCID 0000-0001-6921-4187
Vanderbilt University · US

Funding

Muscarinic modulation of RDoC constructs in primate behavior and fronto-striatal circuitsR01MH129641 · NIMH · VANDERBILT UNIVERSITY · PI Thilo Womelsdorf · 2022 to 2026
$3.3M
NIMH NIH HHS R01 MH129641
6 · The paper itself

Abstract

Background: Understanding the neurobiological substrates of psychiatric disorders requires comprehensive evaluations of cognitive and motivational functions in preclinical research settings. The translational validity of such evaluations will be supported by (1) tasks with high construct validity that are engaging and easy to teach to human and nonhuman participants, (2) software that enables efficient switching between multiple tasks in single sessions, (3) software that supports tasks across a broad range of physical experimental setups, and (4) by platform architectures that are easily extendable and customizable to encourage future optimization and development. New Method: We describe the Results: M-USE was used to test NHPs on up to six tasks per session, all available as part of the Task Library, and to extract performance metrics for all major cognitive and motivational constructs spanning the Research Domain Criteria (RDoC) of the National Institutes of Mental Health. Comparison with Existing Methods: Other experiment design and control systems exist, but do not provide the full range of features available in M-USE, including a pre-existing task library for cross-species assessments; the ability to switch seamlessly between tasks in individual sessions; cross-platform build capabilities; license-free availability; and its leveraging of video-engine capabilities used to gamify tasks. Conclusions: The new multi-task platform facilitates cross-species translational research for understanding the neurobiological substrates of higher cognitive and motivational functions.

Indexed as

Diagnostic Batterynaturalistic behaviornonhuman primatesvideo-enginevirtual reality

Identifiers

PMID38014107
PMCPMC10680597
OpenAlexW4388620288

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.