Evidence map›Paper›PMID 38013967›Full record

ArticleClinical immunology communications2022

Differential peripheral blood mononuclear cell reactivity against SARS-CoV-2 proteins in naïve and previously infected subjects following COVID-19 vaccination.

Elizabete Cristina Iseke Bispo, Amandda Évelin Silva-Carvalho, Marielly Reis Resende Sousa, Francisco de Assis Rocha Neves, Juliana Lott Carvalho, Enrique Roberto Arganaraz, Felipe Saldanha-Araujo

Open access · goldAbstract read
In one paragraph

Article in Clinical immunology communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Considerations on COVID-19 vaccination.Clinical immunology communications · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elizabete Cristina Iseke BispoLaboratório de Hematologia e Células-Tronco, Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Darcy Ribeiro, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Amandda Évelin Silva-CarvalhoLaboratório de Hematologia e Células-Tronco, Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Darcy Ribeiro, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Marielly Reis Resende SousaLaboratório de Hematologia e Células-Tronco, Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Darcy Ribeiro, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Francisco de Assis Rocha NevesLaboratório de Farmacologia Molecular, Faculdade de Ciências da Saúde, Universidade de Brasília, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Juliana Lott CarvalhoLaboratório Interdisciplinar de Biociências, Faculdade de Medicina, Universidade de Brasília, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Enrique Roberto ArganarazLaboratório de Virologia Molecular, Faculdade de Ciências da Saúde, Universidade de Brasília, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Felipe Saldanha-AraujoLaboratório de Hematologia e Células-Tronco, Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Darcy Ribeiro, Av. L2 Norte, Brasília, DF 70.910-900, Brasil.
Universidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The decline in vaccine efficacy and the risk of reinfection by SARS-CoV-2 make new studies important to better characterize the immune response against the virus and its components. Here, we investigated the pattern of activation of T-cells and the expression of inflammatory factors by PBMCs obtained from naïve and previously infected subjects following COVID-19 vaccination, after PBMCs stimulation with S1, RBD, and N-RBD SARS-CoV-2 proteins. PBMCs showed low levels of

Indexed as

NucleocapsidSARS-CoV-2T-cellsVaccination

Identifiers

PMID38013967
PMCPMC9714124
OpenAlexW4310529631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.