Evidence map›Paper›PMID 38013433›Full record

ArticleBiochemistry2024

Correlating Conformational Equilibria with Catalysis in the Electron Bifurcating EtfABCX of

Daniel T Murray, Xiaoxuan Ge, Gerrit J Schut, Daniel J Rosenberg, Michal Hammel, Jan C Bierma, Russ Hille, Michael W W Adams, Greg L Hura

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Biophysical journal · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Daniel T MurrayMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.ORCID 0000-0002-0807-291X
Xiaoxuan GeDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Gerrit J SchutDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Daniel J RosenbergMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Michal HammelMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.ORCID 0000-0002-5610-9289
Jan C BiermaMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Russ HilleDepartment of Biochemistry, University of California, Riverside, Riverside, California 92521, United States.
Michael W W AdamsDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Greg L HuraMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.ORCID 0000-0003-0501-8464
Lawrence Berkeley National Laboratory · USUniversity of Georgia · USUniversity of California, Riverside · US

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
Mechanistic studies of a bifurcating flavoproteinR01GM135088 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI HILLE, RUSS · 2020 to 2023
$1.3M
A Pixel Array Detector System for Small Angle X-ray ScatteringS10OD018483 · OD · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CLASSEN, SCOTT · 2014 to 2014
$998k
NIGMS NIH HHS P30 GM124169NIGMS NIH HHS R01 GM135088NIH HHS S10 OD018483
6 · The paper itself

Abstract

Electron bifurcation (BF) is an evolutionarily ancient energy coupling mechanism in anaerobes, whose associated enzymatic machinery remains enigmatic. In BF-flavoenzymes, a chemically high-potential electron forms in a thermodynamically favorable fashion by simultaneously dropping the potential of a second electron before its donation to physiological acceptors. The cryo-EM and spectroscopic analyses of the BF-enzyme Fix/EtfABCX from

Indexed as

ElectronsThermotoga maritimaCatalysisElectron TransportFlavinsNADOxidation-ReductionScattering, Small AngleX-Ray DiffractionFlavinsNAD

Identifiers

PMID38013433
PMCPMC10765413
OpenAlexW4389091344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.