Evidence map›Paper›PMID 38012719›Full record

ArticleParasites & vectors2023

Efficacy of a chewable tablet containing sarolaner, moxidectin, and pyrantel (Simparica Trio

Csilla Becskei, Julian Liebenberg, Tiago Fernandes, Stasia Borowski, Lina D'Hanis, Sean P Mahabir

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Parasites & vectors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Csilla BecskeiZoetis, Veterinary Medicine Research and Development, Mercuriusstraat 20, B-1930, Zaventem, Belgium. csilla.becskei@zoetis.com.
Julian LiebenbergClinVet International (Pty) Ltd, Uitzich Road, Bainsvlei, 9338, Bloemfontein, Republic of South Africa.
Tiago FernandesZoetis, Veterinary Medicine Research and Development, Mercuriusstraat 20, B-1930, Zaventem, Belgium.
Stasia BorowskiZoetis, Veterinary Medicine Research and Development, Mercuriusstraat 20, B-1930, Zaventem, Belgium.
Lina D'HanisZoetis, Veterinary Medicine Research and Development, Mercuriusstraat 20, B-1930, Zaventem, Belgium.
Sean P MahabirZoetis, Veterinary Medicine Research and Development, 333 Portage St, Kalamazoo, MI, 49007, USA.
Zoetis (Belgium) · BEClinvet · ZAZoetis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfestation with Sarcoptes scabiei in dogs is a debilitating disease if left untreated and is transmissible to humans. Two field studies were conducted to confirm the efficacy of orally administered sarolaner in combination with moxidectin and pyrantel (Simparica Trio

methodsClient-owned dogs with S. scabiei infestation were enrolled and received 2 monthly treatments. In the first, small-scale study, 12 dogs each were allocated randomly to treatment with either placebo or Simparica Trio

resultsIn the small-scale study, 2 monthly doses of Simparica Trio

conclusionsTwo-monthly doses of Simparica Trio

Indexed as

AcaricidesDog DiseasesMite InfestationsScabiesAnimalsAzetidinesDogsIsoxazolesMacrolidesNaphthalenesPyrantelSarcoptes scabieiSpiro CompoundsTabletsTreatment OutcomeAcaricidesafoxolanerAzetidinesIsoxazolesMacrolidesmilbemycin oximemoxidectinNaphthalenesPyrantelsarolanerSpiro CompoundsTabletsDogEfficacyMangeMoxidectinOralPyrantel pamoateSarcoptes scabieiSarcopticSarolanerScabiesSimparica Trio®

Identifiers

PMID38012719
PMCPMC10683308
OpenAlexW4389047501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.