Evidence map›Paper›PMID 38012675›Full record

ArticleRadiation oncology (London, England)2023

A prospective single-arm study on the relationship between dose-volume parameters of pelvic functional bone marrow and acute hematological toxicities during intensity-modulated radiotherapy with or without concurrent chemotherapy for uterine cervical/endometrial cancer.

Hongbo Chen, Qian Zhong, Yujie Liu, Jinyan Li, Wenjing Deng, Jie Wang, Shuquan Zhou, Zengrong Yu, Xianzhan Huang, Yuanqiong Huang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Phenylethanoid Glycosides fromInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Hongbo Chen *Department of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Qian Zhong *Department of Gynecology, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Yujie Liu *Department of Oncology Unit II, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Jinyan LiDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Wenjing DengDepartment of Oncology Unit III, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Jie WangDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Shuquan ZhouDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Zengrong YuDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Xianzhan HuangDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Yuanqiong HuangDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Bo ZhenDepartment of Gynecology, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Jihong WeiDepartment of Gynecology, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Weijian ZhangDepartment of Gynecology, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China.
Xiaohong RuanDepartment of Gynecology, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China. 13924680902@139.com.
Lin XiaoDepartment of Radiotherapy Center, Jiangmen Central Hospital, Jiangmen, Guangdong Province, China. xiaolin7966165@126.com.
Jiangmen Central Hospital · CNShanghai Liangyou (China) · CN

Funding

Medical Science and Technology Research Foundation of Guangdong Province of China A2016623
6 · The paper itself

Abstract

backgroundFLT-PET/CT can accurately identify and locate functional bone marrow (FBM) with hematopoietic capability, the FBM were divided into two levels as FBM

methodsFrom December 2016 to September 2021, ninety-seven uterine cervical/endometrial cancer patients received intensity-modulated radiation therapy were prospectively recruited in this single-arm, prospective, phase II trial. Blood counts were reviewed weekly during radiotherapy. Single- and multifactor regression methods were used to analyze the relationships between dose-volume parameters of FBM

resultsThe incidence of grade ≥ 2 leukopenia, neutropenia, thrombocytopenia and anemia in patients during radiotherapy was 63.9%, 45.4%, 19.6% and 38.8% respectively, and the median occurrence time was the 29th, 42th, 35th and 31th day, respectively. Multivariate regression analysis showed that the D

conclusionsGrade ≥ 2 HT usually occurs in the 4th week of radiotherapy for patients with uterine cervical/endometrial cancer. The D

Indexed as

AnemiaEndometrial NeoplasmsLeukopeniaRadiotherapy, Intensity-ModulatedThrombocytopeniaUterine Cervical NeoplasmsBone MarrowChemoradiotherapyCisplatinFemaleHumansPositron Emission Tomography Computed TomographyProspective StudiesRadiotherapy DosageCisplatinChemoradiotherapyEndometrial cancerFunctional bone marrowHematologic toxicityUterine cervical cancer

Identifiers

PMID38012675
PMCPMC10683159
OpenAlexW4389040578

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.