Evidence map›Paper›PMID 38012660›Full record

ArticleBMC medical ethics2023

Should AI allocate livers for transplant? Public attitudes and ethical considerations.

Max Drezga-Kleiminger, Joanna Demaree-Cotton, Julian Koplin, Julian Savulescu, Dominic Wilkinson

Abstract read
In one paragraph

Article in BMC medical ethics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Exploring the challenges: main contraindications in organ donation in ColombiaBiomedica : revista del Instituto Nacional de Salud · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Beyond generic principles: a framework for the ethical analysis of artificial intelligence in organ transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  10. Article
  11. Shaping the Future of AI in Organ Transplantation: Position Paper of the European Society for Organ Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  12. Article
  13. Review
  14. Review
  15. Ethical frontiers in liver transplantation.World journal of transplantation · 2024
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Max Drezga-KleimingerFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
Joanna Demaree-CottonOxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Oxford, OX1 2JD, UK.
Julian KoplinMonash Bioethics Centre, Monash University, Melbourne, Australia.
Julian SavulescuOxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Oxford, OX1 2JD, UK.
Dominic WilkinsonFaculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia. dominic.wilkinson@philosophy.ox.ac.uk.

Funding

Wellcome TrustWellcome Trust 203132/Z/16/Z
6 · The paper itself

Abstract

backgroundAllocation of scarce organs for transplantation is ethically challenging. Artificial intelligence (AI) has been proposed to assist in liver allocation, however the ethics of this remains unexplored and the view of the public unknown. The aim of this paper was to assess public attitudes on whether AI should be used in liver allocation and how it should be implemented.

methodsWe first introduce some potential ethical issues concerning AI in liver allocation, before analysing a pilot survey including online responses from 172 UK laypeople, recruited through Prolific Academic.

findingsMost participants found AI in liver allocation acceptable (69.2%) and would not be less likely to donate their organs if AI was used in allocation (72.7%). Respondents thought AI was more likely to be consistent and less biased compared to humans, although were concerned about the "dehumanisation of healthcare" and whether AI could consider important nuances in allocation decisions. Participants valued accuracy, impartiality, and consistency in a decision-maker, more than interpretability and empathy. Respondents were split on whether AI should be trained on previous decisions or programmed with specific objectives. Whether allocation decisions were made by transplant committee or AI, participants valued consideration of urgency, survival likelihood, life years gained, age, future medication compliance, quality of life, future alcohol use and past alcohol use. On the other hand, the majority thought the following factors were not relevant to prioritisation: past crime, future crime, future societal contribution, social disadvantage, and gender.

conclusionsThere are good reasons to use AI in liver allocation, and our sample of participants appeared to support its use. If confirmed, this support would give democratic legitimacy to the use of AI in this context and reduce the risk that donation rates could be affected negatively. Our findings on specific ethical concerns also identify potential expectations and reservations laypeople have regarding AI in this area, which can inform how AI in liver allocation could be best implemented.

Indexed as

Artificial IntelligenceLiver TransplantationHumansLiverPublic OpinionQuality of LifeAlgorithmsArtificial intelligenceBioethicsMachine learningOrgan allocationPublic attitudesResource allocationTransplantation

Identifiers

PMID38012660
PMCPMC10683249

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.