ArticleBMC musculoskeletal disorders2023
What is the association between gender and self-perceived health status when controlling for disease-specific conditions? A retrospective data analysis of pre- and post-operative EQ-5D-5L differences in total hip and knee arthroplasty.
Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preoperative anxiety assessment in orthopaedic surgery: a systematic review and meta-analysis.International orthopaedics · 2025Pooled it
- Functional and quality-of-life outcomes after metal-on-polyethylene articulating spacer implantation for periprosthetic knee infection: a retrospective evaluation of a prospectively collected cohort.Archives of orthopaedic and trauma surgery · 2026Observational
- The Effect of Changes in Defecation Posture on Health-Related Quality of Life Among Elderly Habitual Squat-Toilet Users After Total Hip Arthroplasty for Femoral Neck Fracture.Patient preference and adherence · 2026Article
- Health-Related Quality of Life, Body Mass Index and the 10-Metre Walk Test in Patients Awaiting Total Knee or Hip Arthroplasty: A Cross-Sectional Data Analysis with Matched Controls.Life (Basel, Switzerland) · 2025Article
- Connecting the dots: sex, depression, and musculoskeletal health.The Journal of clinical investigation · 2024Review
- Gender health gap pre- and post-joint arthroplasty: identifying affected patient-reported health domains.International journal for equity in health · 2024Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe self-perceived health status of patients undergoing total hip and knee arthroplasty (THA and TKA) might differ post-operatively due to gender, age, or comorbidities. Patient-reported outcome measures (PROMs) such as the EQ-5D-5L measure the self-perceived health status. This study investigates whether the index score of the EQ-5D-5L is a valid tool for interpreting gender differences in outcomes for patients undergoing THA and TKA.
methodsRoutine and PROM-data of elective primary THA or TKA patients in two German hospitals between 2016 and 2018 were analyzed. Univariate analysis with Pearson's chi-square was conducted to identify control variables for gender. To quantify the association between gender and the EQ-5D-5L dimensions, a cumulative odds ordinal logistic regression with proportional odds was conducted.
resultsTwo thousand three hundred sixty-eight THA patients (m = 978; f = 1390) and 1629 TKA patients (m = 715; f = 914) were considered. The regression analysis of the individual EQ-5D-5L dimensions showed that female gender was significantly associated with better self-care (THA and TKA) and better post-operative mobility (THA). In contrast, male gender was significantly associated with less pain/discomfort (TKA) and less anxiety/depression (THA) pre-surgery and 3-months post-surgery.
conclusionOur results confirmed that the self-perceived health status improved after surgery. However, due to the different associations of gender to the individual dimensions of the EQ-5D-5L, the weighted index score clouds the comparability between patients with different gender undergoing THA or TKA. Therefore, we argue to use the individual five dimensions for health status analysis, to reveal relevant additional information.
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