Evidence map›Paper›PMID 38012585›Full record

ArticleBMC cancer2023

Yttrium Oxide nanoparticles induce cytotoxicity, genotoxicity, apoptosis, and ferroptosis in the human triple-negative breast cancer MDA-MB-231 cells.

Basant Emad, Amr Ahmed WalyEldeen, Hebatallah Hassan, Marwa Sharaky, Ismail A Abdelhamid, Sherif Abdelaziz Ibrahim, Hanan Rh Mohamed

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

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  6. Wnt Signaling Downregulation Mediates T Cell Apoptosis Following OKT3-Induced T Cell Activation in Preclinical Models.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  16. YScientific reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Basant Emad *Biotechnology/Biomolecular Chemistry program, Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Amr Ahmed WalyEldeen *Department of Zoology, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Hebatallah Hassan *Department of Zoology, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Marwa SharakyPharmacology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, 11796, Egypt.
Ismail A Abdelhamid *Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Sherif Abdelaziz Ibrahim *Department of Zoology, Faculty of Science, Cairo University, Giza, 12613, Egypt. isherif@cu.edu.eg.
Hanan Rh Mohamed *Department of Zoology, Faculty of Science, Cairo University, Giza, 12613, Egypt. hananeeyra@cu.edu.eg.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriple-negative breast cancer (TNBC) is a lethal mammary carcinoma subtype that affects females and is associated with a worse prognosis. Chemotherapy is the only conventional therapy available for patients with TNBC due to the lack of therapeutic targets. Yttrium oxide (Y

methodsTransmission electron microscopy (TEM), X-ray diffraction, Zeta potential, and dynamic light scattering (DLS) were used to characterize the Y

resultsOur results indicate favorable physiochemical properties of Y

conclusionThis study suggests that Y

Indexed as

FerroptosisNanoparticlesTriple Negative Breast NeoplasmsApoptosisCell Line, TumorDNA DamageFemaleHumansMDA-MB-231 CellsReactive Oxygen SpeciesYttriumReactive Oxygen SpeciesyttriaYttriumApoptosisDNA damageMDA-MB-231ROSTNBCYttrium oxide nanoparticles

Identifiers

PMID38012585
PMCPMC10680179
OpenAlexW4389040100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.