Evidence map›Paper›PMID 38012028›Full record

Observational studyAnnals of family medicine

Home Monitoring of Asthma Exacerbations in Children and Adults With Use of an AI-Aided Stethoscope.

Andrzej Emeryk, Eric Derom, Kamil Janeczek, Barbara Kuźnar-Kamińska, Anna Zelent, Mateusz Łukaszyk, Tomasz Grzywalski, Anna Pastusiak, Adam Biniakowski, Krzysztof Szarzyński and 3 more

Registry-linked trialOpen access · diamondAbstract readObservational Study
In one paragraph

Observational study in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07631377 (The LalelaLung Study), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07631377 phase4not yet recruitingnot on this map

The LalelaLung Study: Digital Stethoscope Clinical Evaluation

TypeinterventionalSponsorJohns Hopkins UniversityRan2026 to 2028Enrolled350ConditionsPneumonia, Tuberculosis, Pulmonary, Respiratory Tract Infections, BronchiolitisArmsStethoMe AI-enabled digital stethoscope system, Standard IMCI assessment
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Audio-based digital biomarkers in diagnosing and managing respiratory diseases: a systematic review and bibliometric analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  4. Chest auscultation - tradition and expectationsScandinavian journal of primary health care · 2026
    Review
  5. Article
  6. Review
  7. Leveraging artificial intelligence for the management of preschool wheeze: A narrative review.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Artificial intelligence in pediatric allergy research.European journal of pediatrics · 2024
    Review
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Andrzej EmerykDepartment of Paediatric Pulmonology and Rheumatology, Faculty of Medicine, Medical University of Lublin, Lublin, Poland (A.E., K.J.).
Eric DeromDepartment of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium (E.D.).
Kamil JaneczekDepartment of Paediatric Pulmonology and Rheumatology, Faculty of Medicine, Medical University of Lublin, Lublin, Poland (A.E., K.J.); kamil.janeczek@umlub.pl.
Barbara Kuźnar-KamińskaDepartment of Pulmonology, Allergology, and Respiratory Oncology, Poznań University of Medical Sciences, Poznań, Poland (B.K.K.).
Anna ZelentDepartment of Pediatric Pneumonology, Allergology, and Clinical Immunology, Poznań University of Medical Sciences, Poznań, Poland (A.Z.).
Mateusz Łukaszyk1st Department of Lung Diseases and Tuberculosis, Faculty of Medicine, Medical University of Bialystok, Białystok, Poland (M.Ł.).
Tomasz GrzywalskiStethoMe Sp. z o.o., Poznań, Poland (T.G., A.P., A.B., K.S., J.K., H.H.D).
Anna PastusiakStethoMe Sp. z o.o., Poznań, Poland (T.G., A.P., A.B., K.S., J.K., H.H.D).
Adam BiniakowskiStethoMe Sp. z o.o., Poznań, Poland (T.G., A.P., A.B., K.S., J.K., H.H.D).
Krzysztof SzarzyńskiStethoMe Sp. z o.o., Poznań, Poland (T.G., A.P., A.B., K.S., J.K., H.H.D).
Dick BotteldoorenWAVES Research Group, Department of Information Technology, Ghent University, Ghent, Belgium (T.G., D.B.).
Jędrzej KocińskiStethoMe Sp. z o.o., Poznań, Poland (T.G., A.P., A.B., K.S., J.K., H.H.D).
Honorata Hafke-DysStethoMe Sp. z o.o., Poznań, Poland (T.G., A.P., A.B., K.S., J.K., H.H.D).
Adam Mickiewicz University in Poznań · PLGhent University · BEMedical University of Lublin · PLPoznan University of Medical Sciences · PLGhent University Hospital · BEMedical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe advent of new medical devices allows patients with asthma to self-monitor at home, providing a more complete picture of their disease than occasional in-person clinic visits. This raises a pertinent question: which devices and parameters perform best in exacerbation detection?

methodsA total of 149 patients with asthma (90 children, 59 adults) participated in a 6-month observational study. Participants (or parents) regularly (daily for the first 2 weeks and weekly for the next 5.5 months, with increased frequency during exacerbations) performed self-examinations using 3 devices: an artificial intelligence (AI)-aided home stethoscope (providing wheezes, rhonchi, and coarse and fine crackles intensity; respiratory and heart rate; and inspiration-to-expiration ratio), a peripheral capillary oxygen saturation (SpO

resultsThe best single-parameter discriminators of exacerbations were wheezes intensity for young children (AUC 84% [95% CI, 82%-85%]), rhonchi intensity for older children (AUC 81% [95% CI, 79%-84%]), and survey answers for adults (AUC 92% [95% CI, 89%-95%]). The greatest efficacy (in terms of AUC) was observed for a combination of several parameters.

conclusionsThe AI-aided home stethoscope provides reliable information on asthma exacerbations. The parameters provided are effective for children, especially those younger than 5 years of age. The introduction of this tool to the health care system might enhance asthma exacerbation detection substantially and make remote monitoring of patients easier.

Indexed as

AsthmaStethoscopesAdolescentAdultArtificial IntelligenceChildChild, PreschoolHumansMachine LearningRespiratory SoundsAI-aided medical deviceasthma exacerbationasthma monitoringchildhood asthmahome health care

Identifiers

PMID38012028
PMCPMC10681685
OpenAlexW4389037480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.