Evidence map›Paper›PMID 38011407›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association2024

Analysis of the risk of future gastrointestinal surgery in Crohn's disease with stricture.

Wen Zeng, Yong Chen, Bolong Yin, Xue Wen, Jian Xiao, Lian Luo, Haiyuan Tang, He Zheng

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
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Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wen ZengDepartment of Scientific Research and Teaching, Central Hospital of Shaoyang, Shaoyan, China.
Yong ChenDepartment of Oncology, Central Hospital of Shaoyang, Shaoyan, China.
Bolong YinDepartment of Scientific Research and Teaching, Central Hospital of Shaoyang, Shaoyan, China.
Xue WenDepartment of Scientific Research and Teaching, Central Hospital of Shaoyang, Shaoyan, China.
Jian XiaoGraduate School, University of South China, China.
Lian LuoDepartment of Oncology, Central Hospital of Shaoyang, Shaoyan, China.
Haiyuan TangDepartment of Neurology and Stroke Center, Central Hospital of Shaoyang, Shaoyan, China.
He ZhengDepartment of Hepatobiliary Surgery, Central Hospital of Shaoyang, Shaoyan, China.
The Central Hospital of Shaoyang · CNUniversity of South China · CNCommunication University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStricture in patients with Crohn's disease (CD) carries a high risk of CD-related surgery in the course of the disease. The aim of this study was to assess the rate of occurrence of CD-related surgery and to determine baseline risk factors predicting subsequent surgery in this patient group.

methodsPatients registered with stricturing CD were included. All baseline and follow-up data were collected retrospectively. Patients attended the clinic for follow-up at week 14 to assess their response to infliximab (IFX). CD-related surgery was the observational endpoint. Univariate and multivariate Cox regression analyses were used.

resultsA total of 123 patients with stricturing CD were included in this study. The cumulative risk of CD-related surgery for years 1-5 after diagnosis was 18.0%, 26.7%, 32.6%, 40.7%, and 46.4%, respectively. Prior gastrointestinal (GI) surgery, low body mass index (BMI), and high platelet count might be risk factors for future CD-related surgery. With 97 participants treated by IFX, prior GI surgery and primary non-response (PNR) to IFX correlated with future CD-related surgery.

conclusionPrior GI surgery, BMI, and platelet counts were related to future CD-related surgery. Patients who were PNR to IFX had a higher risk of CD-related surgery in the future.

Indexed as

Crohn DiseaseDigestive System Surgical ProceduresConstriction, PathologicHumansInfliximabRetrospective StudiesInfliximab

Identifiers

PMID38011407
PMCPMC10980300
OpenAlexW4387940397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.