Evidence map›Paper›PMID 38011132›Full record

ArticlePloS one2023

Impact of the COVID-19 pandemic on routine HIV care and antiretroviral treatment outcomes in Kenya: A nationally representative analysis.

Davies O Kimanga, Valeria N B Makory, Amin S Hassan, Faith Ngari, Margaret M Ndisha, Kennedy J Muthoka, Lydia Odero, Gonza O Omoro, Appolonia Aoko, Lucy Ng'ang'a

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Davies O KimangaDivision for Global HIV & TB (DGHT), Center for Global Health, US Centres for Disease Control and Prevention (CDC), Nairobi, Kenya.ORCID 0000-0001-9326-0407
Valeria N B MakoryNational AIDS and STI Control Program (NASCOP), Ministry of Health, Nairobi, Kenya.
Amin S HassanDepartment of HIV/STI, KEMRI/Wellcome Trust Research Programme, Kilifi, Kenya.
Faith NgariNational AIDS and STI Control Program (NASCOP), Ministry of Health, Nairobi, Kenya.
Margaret M NdishaDivision for Global HIV & TB (DGHT), Center for Global Health, US Centres for Disease Control and Prevention (CDC), Nairobi, Kenya.
Kennedy J MuthokaEpidemiology and Data Use, Palladium Group, Nairobi, Kenya.
Lydia OderoHealth Population and Nutrition, United States Agency for International Development (USAID), Nairobi, Kenya.
Gonza O OmoroStrategic Information, Military HIV Research Program/Walter Reed Army Institute of Research (MHRP/WRAIR), Nairobi, Kenya.
Appolonia AokoDivision for Global HIV & TB (DGHT), Center for Global Health, US Centres for Disease Control and Prevention (CDC), Nairobi, Kenya.
Lucy Ng'ang'aDivision for Global HIV & TB (DGHT), Center for Global Health, US Centres for Disease Control and Prevention (CDC), Nairobi, Kenya.
Centers for Disease Control and Prevention · KEMinistry of Health · KEFutures Group (United States) · USKenya Medical Research Institute · KEUnited States Agency for International Development · USUnited States Army Medical Research Directorate - Africa · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic adversely disrupted global health service delivery. We aimed to assess impact of the pandemic on same-day HIV diagnosis/ART initiation, six-months non-retention and initial virologic non-suppression (VnS) among individuals starting antiretroviral therapy (ART) in Kenya.

methodsIndividual-level longitudinal service delivery data were analysed. Random sampling of individuals aged >15 years starting ART between April 2018 -March 2021 was done. Date of ART initiation was stratified into pre-COVID-19 (April 2018 -March 2019 and April 2019 -March 2020) and COVID-19 (April 2020 -March 2021) periods. Mixed effects generalised linear, survival and logistic regression models were used to determine the effect of COVID-19 pandemic on same-day HIV diagnosis/ART initiation, six-months non-retention and VnS, respectively.

resultsOf 7,046 individuals sampled, 35.5%, 36.0% and 28.4% started ART during April 2018 -March 2019, April 2019 -March 2020 and April 2020 -March 2021, respectively. Compared to the pre-COVID-19 period, the COVID-19 period had higher same-day HIV diagnosis/ART initiation (adjusted risk ratio [95% CI]: 1.09 [1.04-1.13], p<0.001) and lower six-months non-retention (adjusted hazard ratio [95% CI]: 0.66 [0.58-0.74], p<0.001). Of those sampled, 3,296 (46.8%) had a viral load test done at a median 6.2 (IQR, 5.3-7.3) months after ART initiation. Compared to the pre-COVID-19 period, there was no significant difference in VnS during the COVID-19 period (adjusted odds ratio [95% CI]: 0.79 [95%% CI: 0.52-1.20], p = 0.264).

conclusionsIn the short term, the COVID-19 pandemic did not have an adverse impact on HIV care and treatment outcomes in Kenya. Timely, strategic and sustained COVID-19 response may have played a critical role in mitigating adverse effects of the pandemic and point towards maturity, versatility and resilience of the HIV program in Kenya. Continued monitoring to assess long-term impact of the COVID-19 pandemic on HIV care and treatment program in Kenya is warranted.

Indexed as

Anti-HIV AgentsCOVID-19HIV InfectionsAnti-Retroviral AgentsHumansKenyaPandemicsAnti-HIV AgentsAnti-Retroviral Agents

Identifiers

PMID38011132
PMCPMC10681195
OpenAlexW4389043331

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.