Evidence map›Paper›PMID 38010886›Full record

ArticleGut microbes2023

Axin1's mystique in manipulating microbiome amidst colitis.

Shari Garrett, Monica C Asada, Jun Sun

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shari GarrettDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Monica C AsadaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Jun SunDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.ORCID 0000-0001-7465-3133
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

How Vitamin D Receptor Influences Intestinal BarriersR01DK114126 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2018 to 2026
$3.0M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK134343 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2023 to 2026
$3.0M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
Microbiome and intestinal barrier in ALS therapyI01BX004824 · VA · JESSE BROWN VA MEDICAL CENTER · PI SUN, JUN · 2020 to 2025
–
BLRD VA I01 BX004824NIDDK NIH HHS R01 DK105118NIDDK NIH HHS R01 DK114126NIDDK NIH HHS R01 DK134343
6 · The paper itself

Abstract

Classically, Axin1 is considered a regulator of Wnt/β-catenin signaling. However, Axin1's roles in host-microbial interactions have been unknown. Our recent study has demonstrated that deletion of intestinal epithelial Axin1 in epithelial cells and Paneth cells protects the host against colitis by enhancing

Indexed as

Axin ProteinColitisGastrointestinal MicrobiomeMicrobiotaAkkermansiaAnimalsbeta CateninInflammationMicePaneth CellsAxin1 protein, mouseAxin Proteinbeta CateninAxin1Axin2beta-catenincolitisfecal microbiota transplantationGoblet cellsinflammatory bowel diseasemicrobiomePaneth cellsWnt

Identifiers

PMID38010886
PMCPMC10730173
OpenAlexW4389045463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.