Evidence map›Paper›PMID 38010864›Full record

ArticleOrthopaedic surgery2024

The Quality of Life of the Patients with Thoracic Ossification of the Ligamentum Flavum after Surgery Using EQ-5D-5L.

Junhu Li, Zhipeng Deng, Linnan Wang, Lei Wang, Hailing Yang, Xi Yang, Yuemin Song

Abstract read
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Article in Orthopaedic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Midline delta double-door decompression (MDDD), a novel strategy for thoracic ossification of the ligamentum flavum via uni-portal noncoaxial spinal endoscopic surgery (UNSES): a case series.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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5 · Who and what money

Authors and funding

7 authors.

Junhu LiDepartment of Orthopaedic Surgery, Orthopaedic Research Institute, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Zhipeng DengDepartment of Orthopaedic Surgery, Orthopaedic Research Institute, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Linnan WangDepartment of Orthopaedic Surgery, Orthopaedic Research Institute, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.
Lei WangDepartment of Orthopaedic Surgery, Orthopaedic Research Institute, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-2612-8657
Hailing YangProgram in Cellular and Molecular Physiology, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.
Xi YangDepartment of Orthopaedic Surgery, Orthopaedic Research Institute, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-7925-3323
Yuemin SongDepartment of Orthopaedic Surgery, Orthopaedic Research Institute, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is a lack of studies on the quality of life (QoL) after posterior laminectomy in patients with thoracic ossification of the ligamentum flavum (TOLF), and risk factors associated with poor prognosis remain controversial. Therefore, the present study was conducted to illustrate the QoL for TOLF patients after surgery and determine its relationship with their demographic, surgery-related, clinical characteristics and imaging data.

methodsOne hundred and eighteen patients diagnosed with thoracic myelopathy because of TOLF were enrolled in this retrospective study. They all underwent posterior decompressive laminectomy from August 2010 to January 2022. The QoL was evaluated based on the EQ-5D-5L. Collecting gender, age, number of operations, compressed segments, Frankel grade, complications, body mass index (BMI), symptoms and duration, modified Japanese Orthopaedic Association (mJOA) score (preoperative), follow-up time and type of ossification, increased signal on Sagittal T2-weighted Images (ISST2I), occupancy rate and analyzing by Mann-Whitney U-test, Kruskal-Wallis test, the χ

resultsAverage follow-up 70.8 months (18-149), the mean age was 59.74 ± 9.81 years and the mean score for the QoL based on the EQ-5D-5 L and visual analogue scale (VAS) score were 0.71 ± 0.28 and 78.88 ± 10.21 at the final follow-up. Moderate and severe problems were found in the pain/discomfort in 22.0% of the patients. These mobility and usual activities numbers were slightly higher (24.6% and 30.4%, respectively). The mean scores for QoL and VAS were significantly higher in patients with mild and moderate neurological impairment, normal BMI, <60 years of age, no dural tears, symptom relief at hospital discharge, unilateral and bilateral ossification on axial CT scan, ≤ 50% spinal canal occupancy on CT and MRI, and none or fuzzy on ISST2I.

conclusionQoL after posterior laminectomy in TOLF patients is generally satisfactory compared to preoperative levels. Preoperative mJOA score, Age, comorbid diabetes, the major symptom is activity limitation, BMI, ISST2I, Intraoperative dural tears and spinal canal occupancy rate correlate significantly with the corresponding dimensions and are predictive. Age, spinal canal occupancy rate, ISST2I, preoperative mJOA score, BMI are significantly associated with and have predictive value for overall postoperative QoL.

Indexed as

Ligamentum FlavumOssification, HeterotopicAgedDecompression, SurgicalHumansLaminectomyMiddle AgedOsteogenesisQuality of LifeRetrospective StudiesThoracic VertebraeTreatment OutcomeEQ-5D-5 LOssification of the ligamentum flavumPredictive factorsQuality of life

Identifiers

PMID38010864
PMCPMC10782254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.