Evidence map›Paper›PMID 38010777›Full record

ArticleCancer biology & therapy2023

Mathematical modeling predicts pathways to successful implementation of combination TRAIL-producing oncolytic virus and PAC-1 to treat granulosa cell tumors of the ovary.

Justin Le Sauteur-Robitaille, Powel Crosley, Mary Hitt, Adrianne L Jenner, Morgan Craig

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer biology & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Justin Le Sauteur-RobitailleDepartment of Mathematics and Statistics, Université de Montréal, Quebec, Canada.
Powel CrosleyDepartment of Oncology, University of Alberta, Edmonton, Canada.
Mary HittDepartment of Oncology, University of Alberta, Edmonton, Canada.
Adrianne L JennerSchool of Mathematics, Queensland University of Technology, Brisbane, Australia.
Morgan CraigDepartment of Mathematics and Statistics, Université de Montréal, Quebec, Canada.ORCID 0000-0003-4852-4770
Centre Hospitalier Universitaire Sainte-Justine · CAUniversity of Alberta · CAQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of new cancer therapies requires multiple rounds of validation from

Indexed as

Granulosa Cell TumorOncolytic VirotherapyOncolytic VirusesOvarian NeoplasmsAnimalsApoptosisCell Line, TumorFemaleHumansLigandsMiceModels, TheoreticalTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alphaLigandsTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alphaGranulosa cell tumorsmathematical modelingoncolytic virusovarian cancertreatment optimization

Identifiers

PMID38010777
PMCPMC10783843
OpenAlexW4389058123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.