Evidence map›Paper›PMID 38010495›Full record

ArticleArchives of virology2023

Investigation of koala retrovirus in captive koalas with pneumonia and comparative analysis of subtype distribution.

Lipi Akter, Md Abul Hashem, Tofazzal Md Rakib, Md Haroon Or Rashid, Kazi Anowar Hossain, Rupaly Akhter, Masashi Utsunomiya, Bouchra Kitab, Tatsuro Hifumi, Noriaki Miyoshi and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Lipi AkterTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Md Abul HashemTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Tofazzal Md RakibFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.
Md Haroon Or RashidTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Kazi Anowar HossainTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Rupaly AkhterTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Masashi UtsunomiyaTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Bouchra KitabTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan.
Tatsuro HifumiDepartment of Histopathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Noriaki MiyoshiDepartment of Histopathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Fumie MaetaniHirakawa Zoological Park, Kagoshima, Japan.
Kyoko Tsukiyama-KoharaTransboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima, 8900065, Japan. kkohara@vet.kagoshima-u.ac.jp.ORCID http://orcid.org/0000-0002-4403-2018
Kagoshima University · JPChattogram Veterinary and Animal Sciences University · BDTokyo Zoological Park Society · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study focused on the involvement of koala retrovirus (KoRV) in pneumonia in koalas. Three deceased pneumonic koalas from a Japanese zoo were examined in this study. Hematological and histopathological findings were assessed, and KoRV proviral DNA loads in the blood and tissues were compared with those of eight other KoRV-infected koalas from different zoos. Demographic data and routine blood profiles were collected, and blood and tissue samples were analyzed to rule out concurrent infections in pneumonic koalas. KoRV subtyping and measurement of the KoRV proviral DNA load were performed by polymerase chain reaction (PCR) using specific primers targeting the pol and env genes. The results showed that the koalas had histopathologically suppurative and fibrinous pneumonia. Chlamydiosis was not detected in any of the animals. PCR analysis revealed KoRV-A, -B, and -C infections in all koalas, except for animals K10-11, which lacked KoRV-B. Significant variations in the proviral DNA loads of these KoRV subtypes were observed in all tissues and disease groups. Most tissues showed reduced KoRV loads in koalas with pneumonia, except in the spleen, which had significantly higher loads of total KoRV (2.54 × 10

Indexed as

GammaretrovirusPhascolarctidaePneumoniaRetroviridae InfectionsAnimalsDNAProvirusesRetroviridaeDNA

Identifiers

PMID38010495
OpenAlexW4389054498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.