Evidence map›Paper›PMID 38010396›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2024

Therapeutic potential of Lawsonia inermis Linn: a comprehensive overview.

Gaber El-Saber Batiha, John Oluwafemi Teibo, Hazem M Shaheen, Benjamin Ayodipupo Babalola, Titilade Kehinde Ayandeyi Teibo, Hayder M Al-Kuraishy, Ali I Al-Garbeeb, Athanasios Alexiou, Marios Papadakis

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt. gaberbatiha@gmail.com.
John Oluwafemi TeiboDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. johnteibo@usp.br.
Hazem M ShaheenDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt.
Benjamin Ayodipupo BabalolaBiochemistry Division, Department of Chemistry, Purdue University, West Lafayette, IN, 47907, USA.
Titilade Kehinde Ayandeyi TeiboDepartment of Maternal-Infant and Public Health Nursing, College of Nursing, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Hayder M Al-KuraishyDepartment of Clinical Pharmacology and Therapeutic Medicine, College of Medicine, Almustansiriyiah University, Bagh-Dad, Iraq.
Ali I Al-GarbeebDepartment of Clinical Pharmacology and Therapeutic Medicine, College of Medicine, Almustansiriyiah University, Bagh-Dad, Iraq.
Athanasios AlexiouDepartment of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW, 2770, Australia.
Marios PapadakisDepartment of Surgery II, University Hospital Witten-Herdecke, University of Witten-Herdecke, Heusnerstrasse 40, 42283, Wuppertal, Germany. marios_papadakis@yahoo.gr.
Damanhour University · EGPurdue University West Lafayette · USUniversidade de Ribeirão Preto · BRUniversidade de São Paulo · BRWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lawsonia inermis Linn, commonly known as henna, is a member of the Lythraceae family and has been found to contain a variety of compounds with both industrial and medicinal applications in its stem, bark, roots, flowers, and seeds. This report provides a comprehensive review of the bioactive components, pharmacological activities, pharmacokinetics, and pharmacological side effects of Lawsonia inermis. Relevant materials were gathered from Google Scholar, PubMed, Scopus, and Web of Science and reviewed for important properties and updates about the plant. Lawsonia inermis contains a variety of bioactive compounds, including flavonoids, coumarins, triterpenoids, steroids, xanthones, polyphenols, fatty acids, alkaloids, quinones, tannins, leucocyandin, epicatechin, catechin, and quercetin. The plant is been traditionally used to treat numerous conditions, including ulcers, bronchitis, lumbago, hemicrania, leukoderma, scabies, boils, ophthalmic disorders, hair loss, and jaundice. It has also been found to possess a range of pharmacological activities, including antioxidant, anti-inflammatory, analgesic, antiparasitic, hepatoprotective, antifungal, antitumor, wound healing, and hypoglycemic effects. The potential of Lawsonia inermis for various biological applications is promising, and further studies are needed to fully explore its therapeutic benefits for various diseases of public health. Concern advances in drug development could enable the characterization of various bioactive constituents and facilitate their development and application for the benefit of humanity.

Indexed as

Lawsonia PlantPlant ExtractsAnimalsHumansPhytotherapyPlant ExtractsBioactive componentsDrug developmentLawsonia inermisPharmacokineticsPharmacological activitiesPharmacological side effectsTherapeutic benefits

Identifiers

PMID38010396
PMCPMC11111528
OpenAlexW4389051686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.