ArticleMagnetic resonance in medicine2024
Adjustment of rotation and saturation effects (AROSE) for CEST imaging.
Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Inverting CEST orMagnetic resonance in medicine · 2026Article
- CESTsimu: An open-source GUI for spectral and spatial CEST simulation.Magnetic resonance in medicine · 2025Article
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Authors and funding
2 authors.
Funding
Abstract
purposeEndogenous CEST signal usually has low specificity due to contaminations from the magnetization transfer contrast (MTC) and other labile protons with overlapping or close Larmor frequencies. We propose to improve CEST signal specificity with adjustment of rotation and saturation effects (AROSE).
methodsThe AROSE approach measures the difference between CEST signals acquired with the same average irradiation power but largely different duty cycles, for example, a continuous wave or a high duty cycle pulse train versus a low duty cycle pulse train with a flip angle φ. Simulation, phantom, and in vivo rodent studies were performed to evaluate the characteristics of the AROSE
resultsSimulation and experimental results show that AROSE
conclusionCompared to conventional CEST signals, AROSE can minimize MTC and improve exchange rate filtering and Larmor frequency specificity.
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