Evidence map›Paper›PMID 38009710›Full record

ArticleJournal of clinical psychology2024

Mindfulness, coping, and optimism as mechanisms of change in the 3RP-NF intervention.

Victoria A Grunberg, Jafar Bakhshaie, Heena Manglani, Julia Hooker, Elizabeth A Rochon, Ana-Maria Vranceanu

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Victoria A GrunbergCenter for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-3229-5504
Jafar BakhshaieCenter for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Heena ManglaniCenter for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Julia HookerCenter for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Elizabeth A RochonCenter for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Ana-Maria VranceanuCenter for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
Harvard University · USMassachusetts General Hospital · US

Funding

Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
Bridging the Science-to-Service Gap in Aging Care: Prevention, Optimization and Living Well with Persistent or Serious IllnessesT32AG081327 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie, Ana-Maria Vranceanu · 2023 to 2026
$1.6M
Mentoring in technology enhanced mind body and lifestyle interventionsK24AT011760 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI Ana-Maria Vranceanu · 2022 to 2026
$911k
Web-based mind-body treatment to enhance resilience among patients with painful nontraumatic upper extremity conditions and comorbid risky substance useK23AT012364 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI Jafar Bakhshaie · 2023 to 2026
$681k
Resilient Families (R-FAM): A dyadic resiliency intervention for parents of babies in neonatal intensive careK23HD110597 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI Victoria Ann Grunberg · 2023 to 2026
$676k
GINSENG'S EFFECTS ON MRNA PROFILES IN A DIABETES-2 MODELF32AT000051 · NCCIH · UNIVERSITY OF TEXAS AUSTIN · PI PAN, SHUJIA J · 1999 to 2001
$96k
NCCIH NIH HHS F32 AT000051NCCIH NIH HHS K23 AT012364NCCIH NIH HHS K24 AT011760NCCIH NIH HHS T32 AT000051NIA NIH HHS T32 AG081327NICHD NIH HHS K23 HD110597
6 · The paper itself

Abstract

introductionNeurofibromatosis (NF) is chronic neurogenetic condition that increases risk for poor quality of life, depression, and anxiety. Given the lack of biomedical treatments, we developed the "Relaxation Response Resiliency for NF" (3RP-NF) program to improve psychosocial outcomes among adults with NF.

objectiveTo move toward effectiveness testing, we must understand mechanisms that explained treatment effects. We tested whether our hypothesized mechanisms of change-mindfulness, coping, and optimism-mediated improvements in quality of life, depression, and anxiety among adults in the 3RP-NF program (N = 114; ages 18-70; 72.80% female; 81.58% White).

methodsWe conducted mixed-effects models to assess whether these mechanisms uniquely mediated outcomes.

resultsImprovements in quality of life were most explained by coping, (b = 0.97, SE = 0.28, CI [0.45, 1.56]), followed by mindfulness (b = 0.46, SE = 0.17, CI [0.15, 0.82]) and optimism (b = 0.39, SE = 0.12, CI [0.17, 0.65]). Improvements in depression and anxiety were most explained by mindfulness (b = -1.52, SE = 0.38, CI [-2.32, -0.85], CSIE = -0.26; b = -1.29, SE = 0.35, CI [-2.04, -0.67], CSIE = -0.23), followed by optimism (b = 0.39, SE = 0.12, CI [0.17, 0.65]; b = -0.49, SE = 0.20, CI [-0.91, -0.13]), but were not explained by coping (b = 0.22, SE = 0.43, CI [-0.62, 1.07]; b = 0.06, SE = 0.46, CI [-0.84, 0.97]), respectively.

conclusionsTargeting mindfulness, coping, and optimism in psychosocial interventions may be a promising way to improve the lives of adults with NF.

Indexed as

MindfulnessNeurofibromatosesResilience, PsychologicalAdultAnxietyCoping SkillsDepressionFemaleHumansMaleQuality of Lifeanxietydepressionmechanisms of changeneurofibromatosisquality of life

Identifiers

PMID38009710
PMCPMC10896554
OpenAlexW4389037133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.