ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Trends in the prevalence of cognitive impairment at old age in China, 2002-2018.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Magnitude and predictors of mild cognitive impairment among older populations in Africa: a systematic review and meta-analysis.Translational psychiatry · 2025Pooled it
- Chronic Pain and Cognitive Dysfunction: Clinical Implement, Mechanism, and Therapeutic Strategy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- A prospective study of age-related functional impairments, mortality, and life expectancy of Chinese adults aged 50.Communications medicine · 2026Article
- Article
- Mediation by atherogenic index of plasma of the association between body roundness index and cognitive impairment in older Chinese people: an analysis using health check-up data.Frontiers in public health · 2026Article
- Trends in cognitive impairment among older adults in China from 2002 to 2022: Evaluating the impact of the COVID-19 pandemic.The journal of prevention of Alzheimer's disease · 2026Article
- Cognitive decline among Chinese older adults: Findings from the Chinese Longitudinal Healthy Longevity Survey (CLHLS).The journal of prevention of Alzheimer's disease · 2026Article
- Thirty-seven-year trends in the prevalence, incidence, and prognosis of dementia in a Japanese community: the Hisayama study.Alzheimer's research & therapy · 2025Article
- Longitudinal investigation of the HbA1c/HDL-c ratio as a potential biomarker of cognitive decline among Chinese older adults: evidence from CHARLS.BMC public health · 2025Article
- An accessible and efficient mobile eye-tracking application for community-based cognitive impairment screening in China.Alzheimer's research & therapy · 2025Article
- Exploring the association between hemoglobin glycation index and cognitive function in older adults with hypertension: a cross-sectional study.BMC geriatrics · 2025Article
- Predictive value of biliverdin reductase-A and homeostasis model assessment of insulin resistance on mild cognitive impairment in patients with type 2 diabetes.Journal of diabetes investigation · 2025Article
- The relationship between sarcopenia and mental health status in Chinese older adults: the mediating role of activities of daily living.BMC geriatrics · 2025Article
- The influencing factors of cognitive impairment in elderly individuals in Chengdu city: a cross-sectional study based on AD8.BMC geriatrics · 2025Article
- Global burden of Alzheimer's disease and other dementias (1990-2021): inequality, frontier, and decomposition analysis.Frontiers in aging neuroscience · 2025Article
- Trends in the prevalence of cognitive impairment at old age in China, 2002-2018.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
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Authors and funding
13 authors at 11 institutions in 7 countries.
Funding
Abstract
introductionChina has the world's largest number of older adults with cognitive impairment (CI). We aimed to examine secular trends in the prevalence of CI in China from 2002 to 2018.
methodsGeneralized estimating equations (GEE) was used to assess changes in CI trend in 44,154 individuals (72,027 observations) aged 65 to 105 years old.
resultsThe prevalence of CI increased from 2002 to 2008 and then decreased until 2018. The age-standardized prevalence increased from 25.7% in 2002, 26.1% in 2005, to 28.2% in 2008, then decreased to 26.0% in 2011, 25.3% in 2014, and 24.9% in 2018. Females and those ≥ 80 years old had greater CI prevalence. DISCUSSION: The prevalence of CI showed an inverted U shape from early 2000s to late 2010s with a peak in 2008. Follow-up studies are needed to confirm the decreasing trend after 2008 and examine the contributing factors and underlying mechanisms of this trend. HIGHLIGHTS: Generalized estimating equations (GEE) were used to assess trends of changes in cognitive impairment (CI). CI prevalence in China increased from 2002 to 2008 and then decreased until 2018. Females and those ≥ 80 years old had greater CI prevalence. Stroke, diabetes, and cigarette smoking were risk factors for CI.
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