Evidence map›Paper›PMID 38009571›Full record

ArticleGerodontology2024

Proof of concept design for a toothbrush with on-board vacuum to reduce oral aspirates.

Alexandra Griffith, Abhishek Roy, Sahitya Kulkarni, Glennon Simmons, Laura Osorno, Vivek Kumar

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gerodontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra GriffithDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.ORCID https://orcid.org/0009-0006-8288-025X
Abhishek RoyDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.
Sahitya KulkarniDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.
Glennon SimmonsDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.
Laura OsornoDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.
Vivek KumarDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.ORCID https://orcid.org/0000-0001-7536-9281
Rutgers, The State University of New Jersey · US

Funding

New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Bioactive Scaffold for TMJ Disc Regeneration by Endogenous Stem/Progenitor CellsR01DE029321 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEE, CHANG HUN · 2020 to 2024
$3.5M
Diversity Supplement for Angiogenic and anti-microbial supports for pulp regenerationR01DE031812 · NIDCR · UNIVERSITY OF HOUSTON · PI Vivek Kumar · 2022 to 2026
$3.3M
Peptide hydrogels for management and treatment of neovascular posterior segment diseasesR15EY029504 · NEI · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI KUMAR, VIVEK · 2019 to 2020
$508k
Acellular composite hydrogel scaffolds for volumetric muscle regenerationR21AR079708 · NIAMS · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI GRASMAN, JONATHAN M., KUMAR, VIVEK · 2022 to 2023
$467k
National Science FoundationNCATS NIH HHSNCATS NIH HHS UL1 TR003017NEI NIH HHSNEI NIH HHS R15 EY029504NIAMS NIH HHSNIAMS NIH HHS R21 AR079708NIDCR NIH HHSNIDCR NIH HHS R01 DE029321NIDCR NIH HHS R01 DE031812
6 · The paper itself

Abstract

backgroundOver the course of brushing, aerosolised particles develop in the mouth. In individuals who do not have the ability to expel these oral aspirates, they can be inhaled and cause aspiration pneumonia. This article showcases a novel vacuum toothbrush, termed "ToothVac," and provides findings from its first human trial.

methodsThe ToothVac device suctions saliva and aspirates during brushing, storing them in a removable reservoir at the bottom of the brush, to minimise the risk of inhalation and subsequent infection. Further descriptions of the various components of the ToothVac are included. This trial involved 18 participants who brushed using the ToothVac with the vacuum suction turned on and then off.

resultsThe volume of saliva produced was measured and compared. The ToothVac significantly reduced the amount of saliva that was produced by these participants when brushing.

conclusionThe device has potential clinical potential in that it may reduce the risk of aspiration pneumonia and related lung infections. Potential future research may include clinical trials for specific indications or marketing for oral aspirate removal, as well as optimisation of brush design using injection moulding for scalable manufacturing.

Indexed as

Equipment DesignSalivaToothbrushingAdultAgedFemaleHumansMaleMiddle AgedPneumonia, AspirationProof of Concept StudySuctionVacuumaspirationoral devicespneumoniasuctiontoothbrush

Identifiers

PMID38009571
PMCPMC11128478
OpenAlexW4389037322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.