Evidence map›Paper›PMID 38009228›Full record

ArticleAutism research : official journal of the International Society for Autism Research2024

Slower pace in early walking onset is related to communication, motor skills, and adaptive function in autistic toddlers.

Rujuta B Wilson, Emma D Burdekin, Nicholas J Jackson, Lauren Hughart, Jeff Anderson, Stacey C Dusing, Amanda Gulsrud, Connie Kasari

Open access · hybridAbstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  4. Higher Intraindividual Gait Variability in Autistic Toddlers: A Pilot Study.Journal of autism and developmental disorders · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rujuta B WilsonSemel Institute for Neuroscience and Human Behavior, Division of Child Psychiatry, University of California, Los Angeles, California, USA.ORCID 0000-0002-0320-4434
Emma D BurdekinUCLA Department of Pediatrics, Los Angeles, California, USA.
Nicholas J JacksonDepartment of Medicine, Division of General Internal Medicine & Health Services Research, University of California, Los Angeles, California, USA.
Lauren HughartSemel Institute for Neuroscience and Human Behavior, Division of Child Psychiatry, University of California, Los Angeles, California, USA.
Jeff AndersonSemel Institute for Neuroscience and Human Behavior, Division of Child Psychiatry, University of California, Los Angeles, California, USA.
Stacey C DusingOstrow School of Dentistry, Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California, USA.
Amanda GulsrudSemel Institute for Neuroscience and Human Behavior, Division of Child Psychiatry, University of California, Los Angeles, California, USA.ORCID 0000-0001-9537-8601
Connie KasariSemel Institute for Neuroscience and Human Behavior, Division of Child Psychiatry, University of California, Los Angeles, California, USA.ORCID 0000-0003-2266-170X
University of California, Los Angeles · USUniversity of Southern California · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Understanding Repetitive Behavior in AutismP50HD055784 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H · 2007 to 2021
$32.0M
UCLA Center for Translational Research in Neurodevelopment: UC-TRaNU54HD087101 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2016 to 2020
$6.5M
Quantification of Infant Motor Development to Predict Risk for Neurodevelopmental DisordersK23HD099275 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WILSON, RUJUTA BHATT · 2020 to 2024
$887k
NCATS NIH HHS UL1 TR001881NCATS NIH HHS UL1TR001881NICHD NIH HHS K23 HD099275NICHD NIH HHS P50 HD055784NICHD NIH HHS U54 HD087101
6 · The paper itself

Abstract

The onset of walking is a major developmental milestone in early childhood and is critical to the development of language and social communication. Delays in walking have been described in individuals with ASD. Yet, less is known about the quality of early gait development in toddlers with ASD and the relationship to motor skills, social communication, and language. Quantitative measures of locomotion can improve our ability to evaluate subtle and specific motor differences in toddlers with ASD and their relationship to other developmental domains. We used quantitative gait analysis to evaluate locomotion in toddlers with ASD (n = 51) and compared these data to a reference chronological aged (CA) and mental aged (MA) matched typically developing (TD) cohort (n = 45). We also examined the relationship of quantitative gait metrics to developmental measures among toddlers with ASD. We found that although toddlers with ASD achieved a typical age range of walking onset, they exhibited a pattern of slower pace compared to the TD cohort when matched by CA and MA. We also found that slower measures of pace were associated with lower developmental scores of communication, motor skills, and adaptive function. Our findings improve characterization of locomotion in toddlers with ASD and the relationship of motor skills to other developmental domains.

Indexed as

Autism Spectrum DisorderAutistic DisorderChild, PreschoolCommunicationHumansMotor SkillsWalkingautismgaitmotor skillsquantitative measuressocial communication

Identifiers

PMID38009228
PMCPMC10842796
OpenAlexW4389038636

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.