Evidence map›Paper›PMID 38009131›Full record

ArticleHarvard data science review2022

Personalized (N-of-1) Trials for Patient-Centered Treatments of Multimorbidity.

Jerry M Suls, Catherine Alfano, Christina Yap

Open access · hybridAbstract read
In one paragraph

Article in Harvard data science review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jerry M SulsInstitute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health; Manhasset, NY, USA.
Catherine AlfanoInstitute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health; Manhasset, NY, USA.
Christina YapClinical Trials and Statistics Unit, The Institute of Cancer Research; London, UK.
Northwell Health · USInstitute of Cancer Research · GB

Funding

Re-engineering Precision Therapeutics Through N-of-1 TrialsR01LM012836 · NLM · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DAVIDSON, KARINA W. · 2017 to 2023
$7.6M
Roybal Center for Personalized Trials: Physical Activity Promotion to Foster Healthy AgingP30AG063786 · NIA · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI Karina W. Davidson · 2020 to 2026
$6.7M
NIA NIH HHS P30 AG063786NLM NIH HHS R01 LM012836
6 · The paper itself

Abstract

Treatment of patients who suffer from concurrent health conditions is not well served by (1) evidence-based clinical guidelines that mainly specify treatment of single conditions and (2) conventional randomized controlled trials (RCTs) that identify treatments as safe and effective on

Indexed as

cancercomorbiditycoronavirus disease 2019 (COVID-19)multimorbiditypersonalized (N-of-1) trialsrandomized controlled trials (RCTs)

Identifiers

PMID38009131
PMCPMC10673634
OpenAlexW4296141745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.