Evidence map›Paper›PMID 38009093›Full record

ArticleJournal of cancer metastasis and treatment2023

Role of epithelial-mesenchymal transition factor SNAI1 and its targets in ovarian cancer aggressiveness.

Tise Suzuki, Ashlyn Conant, Casey Curow, Audrey Alexander, Yevgeniya Ioffe, Juli J Unternaehrer

Open access · diamondAbstract read
In one paragraph

Article in Journal of cancer metastasis and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tise SuzukiDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Ashlyn ConantDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Casey CurowDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Audrey AlexanderDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Yevgeniya IoffeDepartment of Gynecology and Obstetrics, Division of Gynecologic Oncology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA.
Juli J UnternaehrerDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92354, USA.
Loma Linda University · USLoma Linda University Medical Center · US

Funding

NIH-LLU Initiative for Maximizing Student DiversityR25GM060507 · NIGMS · LOMA LINDA UNIVERSITY · PI DE LEON, MARINO · 2001 to 2022
$11.3M
NIGMS NIH HHS R25 GM060507
6 · The paper itself

Abstract

Ovarian cancer remains the most lethal gynecologic malignancy in the USA. For over twenty years, epithelial-mesenchymal transition (EMT) has been characterized extensively in development and disease. The dysregulation of this process in cancer has been identified as a mechanism by which epithelial tumors become more aggressive, allowing them to survive and invade distant tissues. This occurs in part due to the increased expression of the EMT transcription factor,

Indexed as

cancer aggressivenesscancer invasioncancer stemnesschemoresistanceepithelial-mesenchymal transitionmetastasisovarian cancerSnail

Identifiers

PMID38009093
PMCPMC10673625
OpenAlexW4382600892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.