ArticleBiotechnology for biofuels and bioproducts2023
In situ adsorption of itaconic acid from fermentations of Ustilago cynodontis improves bioprocess efficiency.
Article in Biotechnology for biofuels and bioproducts, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- In situ product removal via reactive extraction in itaconic acid fermentation with Ustilago cynodontis.Biotechnology for biofuels and bioproducts · 2026Article
- From beet molasses to malic acid: holistic development of fermentation and downstream process.Biotechnology for biofuels and bioproducts · 2026Article
- Online Monitoring of Oxygen Transfer Rate as a Versatile Tool for Fermentation Characterization and Optimization.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Integrating pH Value and Base Consumption in Online Monitoring of Organic Acid Production.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Overflow metabolism in bacterial, yeast, and mammalian cells: different names, same game.Molecular systems biology · 2025Review
- Sampling-free investigation of microbial carbon source preferences on renewable feedstocks via online monitoring of oxygen transfer rate.Bioprocess and biosystems engineering · 2025Article
- Online monitoring of methane transfer rates unveils nitrogen fixation dynamics in Methylococcus capsulatus.Biotechnology and bioengineering · 2025Article
- Balancing pH and yield: exploring itaconic acid production in Ustilago cynodontis from an economic perspective.Biotechnology for biofuels and bioproducts · 2024Article
- Phosphate limitation enhances malic acid production on nitrogen-rich molasses with Ustilago trichophora.Biotechnology for biofuels and bioproducts · 2024Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
backgroundReducing the costs of biorefinery processes is a crucial step in replacing petrochemical products by sustainable, biotechnological alternatives. Substrate costs and downstream processing present large potential for improvement of cost efficiency. The implementation of in situ adsorption as an energy-efficient product recovery method can reduce costs in both areas. While selective product separation is possible at ambient conditions, yield-limiting effects, as for example product inhibition, can be reduced in an integrated process.
resultsAn in situ adsorption process was integrated into the production of itaconic acid with Ustilago cynodontis IA
conclusionIntegration of product separation via adsorption into the bioprocess was successfully conducted and improved the efficiency of itaconic acid production. Raman spectroscopy was proven to be a reliable tool for online monitoring of various metabolites and facilitated design and validation of the complex separation and feed process. The general process concept can be transferred to the production of various similar bioproducts, expanding the tool kit for design of innovative biorefinery processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.