Evidence map›Paper›PMID 38007584›Full record

ArticleLeukemia2024

A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia.

Igor Fijalkowski, Jin Wang, Qi Jin, Jolien Van Laere, Valentina Serafin, John D Crispino, Panagiotis Ntziachristos

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Igor Fijalkowski *Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Jin Wang *Health Management Center, Renmin Hospital of Wuhan University, Wuhan, China.
Qi JinDepartment of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.
Jolien Van LaereDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Valentina SerafinPediatric Research Institute Foundation "Città Della Speranza", Padova, Italy.
John D CrispinoDivision of Experimental Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-8182-8306
Panagiotis NtziachristosDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium. pntziachr@gmail.com.ORCID http://orcid.org/0000-0001-6374-8954
Ghent University Hospital · BENorthwestern University · USSt. Jude Children's Research Hospital · USUniversity College Ghent · BEUniversity of Modena and Reggio Emilia · ITWuhan University · CN

Funding

Exploring a new therapeutic approach through targeting epigenetic enzymes in ALLR00CA188293 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NTZIACHRISTOS, PANAGIOTIS · 2015 to 2017
$747k
Therapeutic targeting of demethylation-deubiquitination axis in acute leukemiaR01CA248770 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NTZIACHRISTOS, PANAGIOTIS · 2020 to 2021
$726k
NCI NIH HHS R00 CA188293NCI NIH HHS R01 CA248770
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, T-CellBasic Helix-Loop-Helix ProteinsFeedbackHumansReceptor, Notch1Thiolester HydrolasesBasic Helix-Loop-Helix ProteinsNOTCH1 protein, humanReceptor, Notch1Thiolester HydrolasesUSP11 protein, human

Identifiers

PMID38007584
PMCPMC10776390
OpenAlexW4388999133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.