Evidence map›Paper›PMID 38007477›Full record

ArticleBMC public health2023

The socioeconomic burden of pediatric tuberculosis and role of child-sensitive social protection.

Kinari Shah, Jascent Nakafeero, Jillian L Kadota, Peter Wambi, Gertrude Nanyonga, Emma Kiconco, Atwiine Deus, Moorine P Sekadde, Mary G Nabukenya-Mudiope, Hellen Aanyu- Tukamuhebwa and 6 more

Abstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kinari Shah *Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, CA, USA.
Jascent Nakafeero *Mulago National Referral Hospital, Kampala, Uganda.
Jillian L KadotaDivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, CA, USA.
Peter WambiMulago National Referral Hospital, Kampala, Uganda.
Gertrude NanyongaMulago National Referral Hospital, Kampala, Uganda.
Emma KiconcoMulago National Referral Hospital, Kampala, Uganda.
Atwiine DeusMulago National Referral Hospital, Kampala, Uganda.
Moorine P SekaddeNational TB and Leprosy Program, Ministry of Health, Kampala, Uganda.
Mary G Nabukenya-MudiopeInfectious Diseases Institute, Kampala, Uganda.
Hellen Aanyu- TukamuhebwaMulago National Referral Hospital, Kampala, Uganda.
Ezekiel MupereDepartment of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.
Swomitra MohantyDepartments of Chemical Engineering and Materials Science Engineering, University of Utah, Salt Lake City, Utah, USA.
Adithya CattamanchiDivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, CA, USA.
Eric WobudeyaMulago National Referral Hospital, Kampala, Uganda.
Priya B SheteDivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, CA, USA.
Devan JaganathDivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, CA, USA. devan.jaganath@ucsf.edu.

Funding

Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
Evaluation of a novel breath sensor for rapid, low-cost diagnosis of tuberculosis in childrenR01HL139717 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KATO-MAEDA, MIDORI, MOHANTY, SWOMITRA K · 2018 to 2021
$2.7M
Host Proteomic Biosignatures for a Urine-based Diagnosis of Pulmonary Tuberculosis in ChildrenK23HL153581 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAGANATH, DEVAN · 2020 to 2024
$946k
NHLBI NIH HHS K23 HL153581NHLBI NIH HHS K23HL153581NHLBI NIH HHS R01 HL139717NHLBI NIH HHS R01HL139717NICHD NIH HHS K12 HD000850
6 · The paper itself

Abstract

backgroundHouseholds of children with tuberculosis (TB) experience financial and social hardships, but TB-specific social protection initiatives primarily focus on adults.

methodsWe conducted a single-arm, pilot study of multi-component supportive benefits for children with pulmonary TB in Kampala, Uganda. At diagnosis, participants received in-kind coverage of direct medical costs, a cash transfer, and patient navigation. Caregivers were surveyed before diagnosis and 2 months into TB treatment on social and financial challenges related to their child's illness, including estimated costs, loss of income and dissaving practices.

resultsWe included 368 children from 321 households. Pre-diagnosis, 80.1% of caregivers reported that their child's illness negatively impacted household finances, 44.1% of caregivers missed work, and 24% engaged in dissaving practices. Catastrophic costs (> 20% annual income) were experienced by 18.4% (95% CI 13.7-24.0) of households. School disruption was common (25.6%), and 28% of caregivers were concerned their child was falling behind in development. Two months post-diagnosis, 12 households (4.8%) reported being negatively affected by their child's TB disease (difference -75.2%, 95% CI -81.2 to -69.2, p < 0.001), with limited ongoing loss of income (1.6%) or dissavings practices (0.8%). Catastrophic costs occurred in one household (0.4%) at 2 months post-diagnosis.

conclusionsHouseholds face financial and social challenges prior to a child's TB diagnosis, and child-sensitive social protection support may mitigate ongoing burden.

Indexed as

TuberculosisAdultChildHumansIncomePilot ProjectsPublic PolicyUgandaChildCostSocial protectionTuberculosis

Identifiers

PMID38007477
PMCPMC10675962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.