ReviewJournal of translational medicine2023
Clinical application of calcium silicate-based bioceramics in endodontics.
Review in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Pioneering next-generation bioactive materials for endodontics: Insights of mitochondrial biology.Bioactive materials · 2026Article
- Review
- Novel Midkine-Derived Peptide Promotes Reparative Dentine Formation via DDIT4/mTOR Pathway-Mediated Activation of Autophagy.International endodontic journal · 2026Article
- Tooth discoloration potential of different pulp capping materials in direct and indirect pulp capping procedures: a spectrophotometric in vitro study.BMC oral health · 2026Article
- Aptamer-Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Applications of Nanomaterials in Restorative Dentistry and Endodontics: A Narrative Review.Materials (Basel, Switzerland) · 2026Review
- The Shear Bond Strength Between Calcium Silicate-Based Biomaterials and Glass Ionomer Restorative Materials: An In Vitro Comparative Study.Journal of functional biomaterials · 2026Article
- Effect of Powder-to-Liquid Ratio on pH, Calcium Ion Release, and Solubility Behaviors of Endodontic Bioceramics: An In Vitro Study.Journal of functional biomaterials · 2026Article
- Comparative evaluation of iRoot BP Plus and mineral trioxide aggregate for pulpotomy in primary molars with reversible pulpitis under intraoral endoscope: a retrospective study.BMC oral health · 2026Article
- Calcium Silicate-Based Cements for Vital Pulp Therapy: Integrated Assessment of Radiopacity, Elemental Composition, and 24-h Pulp Cell Responses.Biomimetics (Basel, Switzerland) · 2026Article
- Clinical and radiographic outcomes and associated factors of iRoot BP plus apical barrier treatment in permanent teeth with open apices and periapical lesions: a retrospective study.Clinical oral investigations · 2026Article
- The effect of residual root length and different root canal filling materials on biomechanical stress distribution following apical resection: a finite element analysis study.BMC oral health · 2026Article
- Nonsurgical retrieval of bioceramic materials using ultrasonics: a case report.Journal of medical case reports · 2026Article
- Bioactive Materials and Novel Techniques in Endodontics: Translational Advances for Clinical Practice.Journal of functional biomaterials · 2026Article
- Autologous Dental Pulp Stem Cell Transplantation for Mature Teeth With Apical Periodontitis and Root Perforation: Clinical and Radiographic Outcomes in Two Cases.Case reports in dentistry · 2026Article
- Bioceramics Based on Li-Modified Bioactive Glasses for Bone Tissue Regeneration.Materials (Basel, Switzerland) · 2026Article
- Biomaterials in Restorative Dentistry and Endodontics.Journal of functional biomaterials · 2025Article
- Effect of Ultrasonic Condensation Time on Void Formation and Microhardness of Well-RootMaterials (Basel, Switzerland) · 2025Article
- Bioactivity and biocompatibility of bioceramic-based pulp capping materials in laboratory and animal models.Journal of materials science. Materials in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Pulp treatment is extremely common in endodontics, with the main purpose of eliminating clinical symptoms and preserving tooth physiological function. However, the effect of dental pulp treatment is closely related to the methods and materials used in the process of treatment. Plenty of studies about calcium silicate-based bioceramics which are widely applied in various endodontic operations have been reported because of their significant biocompatibility and bioactivity. Although most of these materials have superior physical and chemical properties, the differences between them can also have an impact on the success rate of different clinical practices. Therefore, this review is focused on the applications of several common calcium silicate-based bioceramics, including Mineral trioxide aggregate (MTA), Biodentine, Bioaggregate, iRoot BP Plus in usual endodontic treatment, such as dental pulp capping, root perforation repair, regenerative endodontic procedures (REPs), apexification, root-end filling and root canal treatment (RCT). Besides, the efficacy of these bioceramics mentioned above in human trials is also compared, which aims to provide clinical guidance for their clinical application in endodontics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.