Evidence map›Paper›PMID 38006335›Full record

ArticleBioinformatics (Oxford, England)2023

Hybkit: a Python API and command-line toolkit for hybrid sequence data from chimeric RNA methods.

Daniel Stribling, Lauren A Gay, Rolf Renne

Open access · goldAbstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Daniel StriblingDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, United States.ORCID 0000-0002-0649-9506
Lauren A GayDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, United States.ORCID 0000-0001-5715-6717
Rolf RenneDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, United States.ORCID 0000-0001-7391-8806
University of Florida Health · USUniversity of Florida · US

Funding

"Project 3" MHV68 IncRNA/miRNA interaction in latency and lympomagenesisP01CA214091 · NCI · UNIVERSITY OF FLORIDA · PI Scott A. Tibbetts · 2017 to 2026
$15.9M
University of Florida Health Cancer Center Support GrantP30CA247796 · NCI · UNIVERSITY OF FLORIDA · PI Alison Ivey · 2023 to 2026
$10.9M
Team-based Interdisciplinary Cancer Research Training ProgramT32CA257923 · NCI · UNIVERSITY OF FLORIDA · PI SIEMANN, DIETMAR W · 2021 to 2025
$1.2M
NCI NIH HHS P01 CA214091NCI NIH HHS P30 CA247796NCI NIH HHS T32 CA257923NIH HHS T32CA257923
6 · The paper itself

Abstract

summaryExperimental methods using microRNA/target ligation have recently provided significant insights into microRNA functioning through generation of chimeric (hybrid) RNA sequences. Here, we introduce Hybkit, a Python3 API, and command-line toolkit for analysis of hybrid sequence data in the "hyb" file format to enable customizable evaluation and annotation of hybrid characteristics. The Hybkit API includes a suite of python objects for developing custom analyses of hybrid data as well as miRNA-specific analysis methods, built-in plotting of analysis results, and incorporation of predicted miRNA/target interactions in Vienna format. AVAILABILITY AND IMPLEMENTATION: Hybkit is provided free and open source under the GNU GPL license at github.com/RenneLab/hybkit and archived on Zenodo (doi.org/10.5281/zenodo.7834299). Hybkit distributions are also provided via PyPI (pypi.org/project/hybkit), Conda (bioconda.github.io/recipes/hybkit/README.html), and Docker (quay.io/repository/biocontainers/hybkit).

Indexed as

MicroRNAsSoftwareResearch DesignMicroRNAs

Identifiers

PMID38006335
PMCPMC10701094
OpenAlexW4388993297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.