Evidence map›Paper›PMID 38005922›Full record

ArticleViruses2023

Does the Presence or a High Titer of Yellow Fever Virus Antibodies Interfere with Pregnancy Outcomes in Women with Zika Virus Infection?

Isa Cristina Ribeiro Piauilino, Raillon Keven Dos Santos Souza, Maurício Teixeira Lima, Yanka Karolinna Batista Rodrigues, Luís Felipe Alho da Silva, Ayrton Sena Gouveia, Alexandre Vilhena da Silva Neto, Bárbara Aparecida Chaves, Maria das Graças Costa Alecrim, Camila Helena Aguiar Bôtto de Menezes and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Isa Cristina Ribeiro PiauilinoPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.
Raillon Keven Dos Santos SouzaFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus 6904-000, Brazil.ORCID 0009-0008-4434-9040
Maurício Teixeira LimaFundação Ezequiel Dias, Belo Horizonte 30510-010, Brazil.ORCID 0000-0002-0830-3909
Yanka Karolinna Batista RodriguesPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.
Luís Felipe Alho da SilvaPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.
Ayrton Sena GouveiaPrograma de Pós-graduação em Biologia Parasitária, Instituto Oswaldo Cruz, Rio de Janeiro 21040-360, Brazil.
Alexandre Vilhena da Silva NetoPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.
Bárbara Aparecida ChavesFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus 6904-000, Brazil.ORCID 0000-0003-2079-6096
Maria das Graças Costa AlecrimPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.
Camila Helena Aguiar Bôtto de MenezesPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.ORCID 0000-0001-6867-4931
Márcia da Costa CastilhoFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus 6904-000, Brazil.
Djane Clarys Baia-da-SilvaPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.
Flor Ernestina Martinez EspinosaPrograma de Pós-Graduação em Medicina Tropical (PPGMT), Universidade do Estado do Amazonas (UEA), Manaus 6904-000, Brazil.ORCID 0000-0002-0325-3674
Fundação de Medicina Tropical · BREzequiel Dias Foundation · BRFundação Oswaldo Cruz · BR

Funding

Fundação de Amparo à Pesquisa do Estado do Amazonas (FAPEAM) xxx
6 · The paper itself

Abstract

Zika virus (ZIKV) and yellow fever virus (YFV) originated in Africa and expanded to the Americas, where both are co-circulated. It is hypothesized that in areas of high circulation and vaccination coverage against YFV, children of pregnant women have a lower risk of microcephaly. We evaluated the presence and titers of antibodies and outcomes in women who had ZIKV infection during pregnancy. Pregnancy outcomes were classified as severe, moderate, and without any important outcome. An outcome was defined as severe if miscarriage, stillbirth, or microcephaly occurred, and moderate if low birth weight and/or preterm delivery occurred. If none of these events were identified, the pregnancy was defined as having no adverse effects. A sample of 172 pregnant women with an acute ZIKV infection confirmed during pregnancy were collected throughout 2016. About 89% (150 of 169) of them presented immunity against YFV, including 100% (09 of 09) of those who had severe outcomes, 84% (16 of 19) of those who had moderate outcomes, and 89% (125 of 141) of those who had non-outcomes. There was no difference between groups regarding the presence of anti-YFV antibodies (

Indexed as

MicrocephalyZika VirusZika Virus InfectionAntibodies, ViralChildFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeYellow fever virusAntibodies, Viralarboviruscongenital Zika virus syndromenon-microcephalic childrenyellow fever virusyellow fever virus vaccineZika virus

Identifiers

PMID38005922
PMCPMC10675107
OpenAlexW4388635800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.