Investigating the Role of Anti-TPO Antibodies in HIV-Associated Thrombocytopenia before and after Initiation of HAART: A Case-Control Longitudinal Study.

Aristotelis Tsiakalos, John G Routsias, Georgios Schinas, Sarah Georgiadou, Nikolaos V Sipsas, Karolina Akinosoglou

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Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact, top 61% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Aristotelis TsiakalosLeto General, Maternity & Gynecology Clinic, 11524 Athens, Greece.

John G RoutsiasDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Georgios SchinasSchool of Medicine, University of Patras, 26504 Rio, Greece.ORCID 0000-0001-7963-1865

Sarah GeorgiadouDepartment of Medicine and Research Laboratory of Internal Medicine, General University Hospital of Larissa, 41110 Larissa, Greece.

Nikolaos V SipsasLaiko General Hospital of Athens and Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-6955-3453

Karolina AkinosoglouSchool of Medicine, University of Patras, 26504 Rio, Greece.ORCID 0000-0002-4289-9494

National and Kapodistrian University of Athens · GRUniversity of Patras · GRLETO Maternity Hospital · GRUniversity Hospital of Larissa · GR

Funding

National and Kapodistrian University of Athens Special Account for Research Funds

6 · The paper itself

Abstract

This longitudinal, case-control study aimed to investigate the role of thrombopoietin (TPO) and anti-TPO antibodies in HIV-associated thrombocytopenia, focusing on the changes seen before and after the initiation of highly active antiretroviral therapy (HAART). Patients were assessed before and at least six months after the initiation of HAART. In total, 75 PLWHIV (age/sex-matched and randomized at 2:1, according to thrombocytopenia status) were included in this study. The baseline assessment revealed significantly higher TPO levels in thrombocytopenic patients (140.45 vs. 106.8 mg/mL,

Indexed as

HIV InfectionsThrombocytopeniaAntiretroviral Therapy, Highly ActiveCase-Control StudiesHumansLongitudinal Studiesanti-thrombopoietin antibodieshighly active antiretroviral therapy (HAART)HIV-1platelet countthrombocytopenia

Identifiers

PMID38005902

DOI10.3390/v15112226

PMCPMC10675467

OpenAlexW4388494865

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.