Evidence map›Paper›PMID 38005862›Full record

ArticleViruses2023

Predictive Model for Mortality in Severe COVID-19 Patients across the Six Pandemic Waves.

Nazaret Casillas, Antonio Ramón, Ana María Torres, Pilar Blasco, Jorge Mateo

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nazaret CasillasDepartment of Internal Medicine, Hospital Virgen De La Luz, 16002 Cuenca, Spain.
Antonio RamónDepartment of Pharmacy, General University Hospital, 46014 Valencia, Spain.ORCID 0000-0002-4273-1990
Ana María TorresMedical Analysis Expert Group, Institute of Technology, University of Castilla-La Mancha, 16002 Cuenca, Spain.
Pilar BlascoDepartment of Pharmacy, General University Hospital, 46014 Valencia, Spain.
Jorge MateoMedical Analysis Expert Group, Institute of Technology, University of Castilla-La Mancha, 16002 Cuenca, Spain.
Hospital General Universitario De Valencia · ESUniversity of Castilla-La Mancha · ESHospital Virgen de la Luz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of SARS-CoV-2 infection remains substantial on a global scale, despite widespread vaccination efforts, early therapeutic interventions, and an enhanced understanding of the disease's underlying mechanisms. At the same time, a significant number of patients continue to develop severe COVID-19, necessitating admission to intensive care units (ICUs). This study aimed to provide evidence concerning the most influential predictors of mortality among critically ill patients with severe COVID-19, employing machine learning (ML) techniques. To accomplish this, we conducted a retrospective multicenter investigation involving 684 patients with severe COVID-19, spanning from 1 June 2020 to 31 March 2023, wherein we scrutinized sociodemographic, clinical, and analytical data. These data were extracted from electronic health records. Out of the six supervised ML methods scrutinized, the extreme gradient boosting (XGB) method exhibited the highest balanced accuracy at 96.61%. The variables that exerted the greatest influence on mortality prediction encompassed ferritin, fibrinogen, D-dimer, platelet count, C-reactive protein (CRP), prothrombin time (PT), invasive mechanical ventilation (IMV), PaFi (PaO

Indexed as

COVID-19HumansIntensive Care UnitsPandemicsRespiration, ArtificialRetrospective StudiesSARS-CoV-2coagulation disorderCOVID-19cytokine release syndromemachine learningSARS-CoV-2XGB

Identifiers

PMID38005862
PMCPMC10675561
OpenAlexW4388108617

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.