ArticleViruses2023
Evidence of Porcine Circovirus Type 2 (PCV2) Genetic Shift from PCV2b to PCV2d Genotype in Sardinia, Italy.
Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The Prevalence and Genetic Diversity of Porcine Circoviruses (PCVs) in Eastern China During 2010-2016 and 2023-2024.Veterinary sciences · 2026Article
- Molecular Variation in Porcine Circovirus Type 2 in Jalisco, Mexico, and Its Potential Impact on Vaccine Efficacy.Vaccines · 2026Article
- Porcine circovirus 2-genotypes in fetuses from litters suspicious for stillbirth, mummification, and embryonic death syndrome (SMEDI) in Germany.Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere · 2026Article
- Molecular Surveillance and Evolutionary Dynamics of Porcine Circovirus Types 2 and 3 in China, 2022-2025.Transboundary and emerging diseases · 2026Article
- Efficacy of a Novel PCV2d andVaccines · 2025Article
- Update on the Prevalence of the PCV2 Major Genotypes PCV2a, PCV2b, and PCV2d in German Fattening Farms in 2024.Veterinary sciences · 2025Article
- Article
- Molecular Positivity of Porcine Circovirus Type 2 Associated with Production Practices on Farms in Jalisco, Mexico.Viruses · 2024Article
- Article
- Genetic diversity of porcine circoviruses 2 and 3 circulating among wild boars in the Moscow Region of Russia.Frontiers in veterinary science · 2024Article
- Global Challenges and Advancements in the Management of Pivotal Porcine/Swine Viral Diseases.In vivo (Athens, Greece)Review
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Authors and funding
12 authors.
Funding
Abstract
Porcine Circovirus type 2 (PCV2) is the etiological agent of a disease syndrome named Porcine Circovirus disease (PCVD), representing an important threat for the pig industry. The increasing international trade of live animals and the development of intensive pig farming seem to have sustained the spreading of PCVD on a global scale. Recent classification criteria allowed the identification of nine different PCV2 genotypes (PCV2a-i). PCV2a was the first genotype detected with the highest frequency from the late 1990s to 2000, which was then superseded by PCV2b (first genotype shift). An ongoing genotype shift is now determining increasing prevalence rates of PCV2d, in replacement of PCV2b. In Italy, a complete genotype replacement was not evidenced yet. The present study was carried out on 369 samples originating from domestic pigs, free-ranging pigs, and wild boars collected in Sardinia between 2020 and 2022, with the aim to update the last survey performed on samples collected during 2009-2013. Fifty-seven complete ORF2 sequences were obtained, and the phylogenetic and network analyses evidenced that 56 out of 57 strains belong to the PCV2d genotype and only one strain to PCV2b, thus showing the occurrence of a genotype shift from PCV2b to PCV2d in Sardinia.
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