Proliferation, Migration and Invasion of Breast Cancer Cell Lines Are Inhibited by 1,5-Disubstituted Tetrazol-1,2,3-triazole Hybrids through Interaction with p53.
Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors at 3 institutions in 1 country.
Marisol Moreno-PereaLaboratorio de microRNAs y Cáncer, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Agronómica, Campus II, Zacatecas 98066, Zacatecas, Mexico.
Abel Suárez-CastroLaboratorio de Diseño Molecular, Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58033, Michoacán, Mexico.ORCID 0000-0002-7916-3640
Ixamail Fraire-SotoLaboratorio de microRNAs y Cáncer, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Agronómica, Campus II, Zacatecas 98066, Zacatecas, Mexico.
Jessica Lizbeth Sifuentes-PadillaLaboratorio de microRNAs y Cáncer, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Agronómica, Campus II, Zacatecas 98066, Zacatecas, Mexico.
Rosalinda Gutiérrez-HernándezUnidad Académica de Enfermería, Universidad Autónoma de Zacatecas, Campus Siglo XXI, Edificio L-1, Segundo Piso, Carretera Zacatecas-Guadalajara Km 6, Ejido La Escondida, Zacatecas 98160, Zacatecas, Mexico.ORCID 0000-0001-6803-925X
Claudia Araceli Reyes-EstradaMaestría en Ciencias de la Salud con Especialidad en Salud Pública, Unidad Academica de Medicina Human, UAZ, Campus Siglo XXI, Edificio L-1, Segundo Piso, Carretera Zacatecas-Guadalajara Km 6, Ejido La Escondida, Zacatecas 98160, Zacatecas, Mexico.
Yamilé López-HernándezLaboratorio de Metabolómica y Proteómica, Cátedra CONACYT, Unidad Académica de Ciencias Biológicas, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Agronómica, Campus II, Zacatecas 98066, Zacatecas, Mexico.ORCID 0000-0002-1068-603X
Carlos J Cortés-GarcíaLaboratorio de Diseño Molecular, Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58033, Michoacán, Mexico.ORCID 0000-0003-4632-6316
Luis Chacón-GarcíaLaboratorio de Diseño Molecular, Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58033, Michoacán, Mexico.ORCID 0000-0001-8877-4817
Angelica Judith Granados-LópezLaboratorio de microRNAs y Cáncer, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Agronómica, Campus II, Zacatecas 98066, Zacatecas, Mexico.
Jesús Adrián LópezLaboratorio de microRNAs y Cáncer, Universidad Autónoma de Zacatecas, Av. Preparatoria S/N, Agronómica, Campus II, Zacatecas 98066, Zacatecas, Mexico.ORCID 0000-0001-8012-7041
Universidad Autónoma de Zacatecas "Francisco García Salinas" · MXUniversidad Michoacana de San Nicolás de Hidalgo · MXSecretaría de Ciencia, Humanidades, Tecnología e Innovación · MX
Funding
Consejo Nacional de Humanidades, Ciencias y Tecnologías FOPO2-2021-04-317425Consejo Nacional de Humanidades, Ciencias y Tecnologías FOPO2-2022-02-321616Consejo Nacional de Humanidades, Ciencias y Tecnologías FORDECYT-PRONACES/610286/2020Consejo Nacional de Humanidades, Ciencias y Tecnologías I1200/320/2022
6 · The paper itself
Abstract
The anticarcinogenic potential of a series of 1,5-disubstituted tetrazole-1,2,3-triazole hybrids (T-THs) was evaluated in the breast cancer (BC)-derived cell lines MCF-7 (ER+, PR+, and HER2-), CAMA-1 (ER+, PR+/-, and HER2-), SKBR-3 (ER+, PR+, and HER2+), and HCC1954 (ER+, PR+, and HER2+). The T-THs
Indexed as
Breast NeoplasmsCell Line, TumorCell ProliferationFemaleHumansMCF-7 CellsMolecular Docking SimulationTriazolesTumor Suppressor Protein p53TriazolesTumor Suppressor Protein p531,4-disubstituted-1,2,3-triazoles1,5-disubstituted tetrazolecell invasioncell migrationcell proliferationhybrid compounds
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Proliferation, Migration and Invasion of Breast Cancer Cell Lines Are Inhibited by 1,5-Disubstituted Tetrazol-1,2,3-triazole Hybrids through Interaction with p53. · full record | OpenQuestion