Evidence map›Paper›PMID 38005217›Full record

ArticleMolecules (Basel, Switzerland)2023

Quercetin-1,2,3-Triazole Hybrids as Multifunctional Anti-Alzheimer's Agents.

Elisabete P Carreiro, Ana R Costa, Célia M Antunes, Sofia Ernesto, Flávia Pinto, Beatriz Rodrigues, Anthony J Burke

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Quercetin Hybrids and their Biological Potential.Mini reviews in medicinal chemistry · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elisabete P CarreiroInstitute for Research and Advanced Training (IIFA), LAQV-REQUIMTE, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.ORCID 0000-0001-8117-7737
Ana R CostaDepartment of Medical and Health Sciences, School of Health and Human Development, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.ORCID 0000-0003-3854-9130
Célia M AntunesDepartment of Medical and Health Sciences, School of Health and Human Development, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.ORCID 0000-0001-8906-1085
Sofia ErnestoDepartment of Chemistry and Biochemistry, School of Sciences and Technologies, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.
Flávia PintoDepartment of Chemistry and Biochemistry, School of Sciences and Technologies, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.
Beatriz RodriguesDepartment of Chemistry and Biochemistry, School of Sciences and Technologies, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.
Anthony J BurkeDepartment of Chemistry and Biochemistry, School of Sciences and Technologies, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.ORCID 0000-0001-8248-1116
University of Évora · PT

Funding

Fundação para a Ciência e Tecnologia LAQV-REQUIMTE (FCT/ MCTES; UIDB/50006/2020|UIDP/50006/2020)
6 · The paper itself

Abstract

The number of patients with Alzheimer's disease (AD) continues to rise and, despite the efforts of researchers, there are still no effective treatments for this multifaceted disease. The main objective of this work was the search for multifunctional and more effective anti-Alzheimer agents. Herein, we report the evaluation of a library of quercetin-1,2,3-triazole hybrids (

Indexed as

Alzheimer DiseaseNeuroprotective AgentsAcetylcholinesteraseCholinesterase InhibitorsDrug DesignGalantamineHumansHydrogen PeroxideQuercetinStructure-Activity RelationshipAcetylcholinesteraseCholinesterase InhibitorsGalantamineHydrogen PeroxideNeuroprotective AgentsQuercetin1,2,3-triazoleAlzheimer’s diseasesantioxidant assaycholinesterase inhibitory assayshybridsquercetinROS protectiontoxicity

Identifiers

PMID38005217
PMCPMC10673615
OpenAlexW4388536646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.