Evidence map›Paper›PMID 38005058›Full record

ReviewMaterials (Basel, Switzerland)2023

Applications of Silk Fibroin in Human and Veterinary Medicine.

Piotr Koczoń, Alicja Dąbrowska, Ewa Laskowska, Małgorzata Łabuz, Katarzyna Maj, Jakub Masztakowski, Bartłomiej J Bartyzel, Andrzej Bryś, Joanna Bryś, Eliza Gruczyńska-Sękowska

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Piotr KoczońDepartment of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences, 159C, Nowoursynowska St., 02-776 Warsaw, Poland.ORCID 0000-0002-8449-6933
Alicja DąbrowskaThe Scientific Society of Veterinary Medicine Students, Warsaw University of Life Sciences, 159, Nowoursynowska St., 02-776 Warsaw, Poland.
Ewa LaskowskaThe Scientific Society of Veterinary Medicine Students, Warsaw University of Life Sciences, 159, Nowoursynowska St., 02-776 Warsaw, Poland.
Małgorzata ŁabuzThe Scientific Society of Veterinary Medicine Students, Warsaw University of Life Sciences, 159, Nowoursynowska St., 02-776 Warsaw, Poland.
Katarzyna MajThe Scientific Society of Veterinary Medicine Students, Warsaw University of Life Sciences, 159, Nowoursynowska St., 02-776 Warsaw, Poland.
Jakub MasztakowskiThe Scientific Society of Veterinary Medicine Students, Warsaw University of Life Sciences, 159, Nowoursynowska St., 02-776 Warsaw, Poland.
Bartłomiej J BartyzelDepartment of Morphological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 159, Nowoursynowska St., 02-776 Warsaw, Poland.ORCID 0000-0002-0175-0706
Andrzej BryśDepartment of Fundamental Engineering and Energetics, Institute of Mechanical Engineering, Warsaw University of Life Sciences, 164, Nowoursynowska St., 02-787 Warsaw, Poland.ORCID 0000-0001-9429-676X
Joanna BryśDepartment of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences, 159C, Nowoursynowska St., 02-776 Warsaw, Poland.ORCID 0000-0002-7852-3624
Eliza Gruczyńska-SękowskaDepartment of Chemistry, Institute of Food Sciences, Warsaw University of Life Sciences, 159C, Nowoursynowska St., 02-776 Warsaw, Poland.ORCID 0000-0003-3309-9425
Warsaw University of Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The properties of silk make it a promising material for medical applications, both in human and veterinary medicine. Its predominant amino acids, glycine and alanine, exhibit low chemical reactivity, reducing the risk of graft rejection, a notable advantage over most synthetic polymers. Hence, silk is increasingly used as a material for 3D printing in biomedicine. It can be used to build cell scaffolding with the desired cytocompatibility and biodegradability. In combination with gelatine, silk can be used in the treatment of arthritis, and as a hydrogel, to regenerate chondrocytes and mesenchymal cells. When combined with gelatine and collagen, it can also make skin grafts and regenerate the integumentary system. In the treatment of bone tissue, it can be used in combination with polylactic acid and hydroxyapatite to produce bone clips having good mechanical properties and high immunological tolerance. Furthermore, silk can provide a good microenvironment for the proliferation of bone marrow stem cells. Moreover, research is underway to produce artificial blood vessels using silk in combination with glycidyl methacrylate. Silk vascular grafts have demonstrated a high degree of patency and a satisfactory degree of endothelial cells coverage.

Indexed as

bone tissue regenerationcartilage regenerationcombinationsmedicinepolymersproteinssilkvascular surgeryveterinarywound healing

Identifiers

PMID38005058
PMCPMC10672237
OpenAlexW4388634412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.